Results 171 to 180 of about 8,076,620 (303)

Induced Pluripotent Stem Cells in Non-Model Species: Applications and Challenges. [PDF]

Cells
Bao Q, Tay NL, Lim CY, Xie S, Ng SC, Pomp O.   +5 more
europepmc   +1 more source

A Robust Deep Temporal Causal Discovery Platform for Single‐Cell Gene Regulatory Network Reconstruction

Advanced Intelligent Discovery, EarlyView.
scTIGER2.0 is a deep‐learning framework that infers gene regulatory networks from single‐cell RNA sequencing data. By integrating correlation, pseudotime ordering, deep learning and bootstrap‐based significance testing, it reduces false positives and reveals directional gene interactions.
Nishi Gupta, Madison Dautle, Shaoqiang Zhang, Yong Chen   +3 more
wiley   +1 more source

Generation of hypoimmunogenic cardiomyocytes from human induced pluripotent stem cells with TAPBP knockout. [PDF]

iScience
Yamamoto Y, Ohno R, Shoda K, Suzuki T, Momoi K, Fujii S, Kenmochi Y, Yoshikawa T, Shimomura M, Tsukamoto N, Ohnuki K, Tani H, Soma Y, Fukuda K, Nakatsura T, Tohyama S.   +15 more
europepmc   +1 more source

A Generative AI Framework to Predict Cardiomyocyte Contraction Function From Single Static Images

Advanced Intelligent Discovery, EarlyView.
A single static hiPSC‐cardiomyocyte image is fed into a U‐Net‐GAN framework, which directly predicts a pixel‐resolved contraction heatmap without time‐lapse imaging. StyleGAN2‐generated synthetic cell–heatmap pairs augment training, improving prediction fidelity (SSIM = 0.84).
Andrew Kowalczewski, Chenyan Wang, Xinrui Wang, Huaxiao Yang, Zhao Qin, Zhen Ma   +5 more
wiley   +1 more source

Urine-derived induced pluripotent stem cells for non-invasive diagnosis of bladder cancer. [PDF]

J Cancer
Zhu Y, Shang J, Zhang X, Tu S, Li G, Li S, Peng H, Ma H, Chen F, Xiang W, Zou C, Xiao Y, Xu Z, Qian K, Wang G.   +14 more
europepmc   +1 more source

The expansion of human induced pluripotent stem cells towards allogeneic cell therapies

THE EXPANSION OF HUMAN INDUCED PLURIPOTENT STEM CELLS TOWARDS ALLOGENEIC CELL THERAPIES The expansion of human induced pluripotent stem cells towards allogeneic cell therapies / Teale, Misha Alexander (Rights reserved) (-
Teale, Misha Alexander
core  

ViTAMIn‐O: Democratizing Computer Vision‐Based Machine Learning for Stem Cell Research

Advanced Intelligent Systems, EarlyView.
This study introduces a fully open generalist computer vision model for predicting the differentiation outcomes of stem cell‐based model systems, together with its code‐free deployment platform, ColabViTAMIn‐O. It is benchmarked against various architectures, datasets, and training protocols.
Ferhat Hamurcu, Markus Breunig, Arpad Varga, Bianka Bosch, Jessica Lindenmayer, Anjan T. Kanakappady, Kevin Achberger, Natalia Pashkovskaia, Alexander Kleger, Stefan Liebau, Stefanie Klingenstein, Moritz Klingenstein   +11 more
wiley   +1 more source

Genetics of growth rate in induced pluripotent stem cells. [PDF]

Stem Cell Reports
Lee BN, Taylor HJ, Cipriani F, Narisu N, Robertson CC, Swift AJ, Sinha N, Yan T, Bonnycastle LL, Dale N, Butt A, Parsaud H, Semrau S, NYSCF Global Stem Cell Array Team, GENESiPS Consortium, iPSCORE Consortium, Knowles JW, Carcamo-Orive I, D'Antonio-Chronowska A, Frazer KA, Biesecker LG, Noggle S, Erdos MR, Paull D, Collins FS, Taylor DL.   +25 more
europepmc   +1 more source

Engineering Intelligent iPSC Biomanufacturing: Integrating Robotic Automation, AI, and Process Control

Advanced Intelligent Systems, EarlyView.
This review highlights recent advances in automated iPSC culture systems integrating robotics, advanced imaging, artificial intelligence, and process control. These technologies improve reproducibility, scalability, and quality in cell expansion, differentiation, and real‐time monitoring, while emerging AI‐enabled and closed‐loop approaches offer new ...
Hyoryong Lee, Roma Desai, Byunggik Kim, Deok‐Ho Kim   +3 more
wiley   +1 more source

Modeling of Lowe Patient-Derived Induced Pluripotent Stem Cells Into Trabecular Meshwork. [PDF]

Am J Ophthalmol
Sun Y, Kowal TJ, Shen Y, Zhao J, Wang B, Lo CH, Lachman HM.   +6 more
europepmc   +1 more source