Generation of induced pluripotent stem cells from a patient with CHARGE syndrome with athymia, harboring a heterozygous mutation in CHD7. [PDF]
Zhao J +6 more
europepmc +1 more source
Rethinking Plasticity in Sponges
This systematic review critiques the conceptual confusion caused by the indiscriminate use of “plasticity” in Porifera literature, revealing that researchers often overlook genetic variability and fail to distinguish between real‐time environmental responses and natural selection.
Laura Oliveira, Emilio Lanna
wiley +1 more source
Impact of differentiation protocols on the functionality of mesenchymal stem cells derived from induced pluripotent stem cells. [PDF]
Ababneh NA +16 more
europepmc +1 more source
Abstract In recent years, the clinical treatment and symptom management of neurological disorders have faced significant challenges due to the high complexity of the nervous system's structure and function. Against this backdrop, physical stimulation techniques have emerged as a vital complementary approach to traditional pharmacological treatments and
Wanying Li, Liqun Chen
wiley +1 more source
A Nanoformulation of Ubiquinol and Selenium Promotes Proliferation of Human Induced Pluripotent Stem Cells. [PDF]
Nguemo F +5 more
europepmc +1 more source
Endothelial Hydrogels Improve Microvascular Regeneration and Perfusion in Tracheal Scaffolds
Insufficient vascularization remains a major barrier to successful tracheal transplantation. This study demonstrates that an endothelial hydrogel significantly enhances graft perfusion and neovessel organization compared to non‐endothelial hydrogel controls.
Molly O. Hunter +6 more
wiley +1 more source
Lithium chloride suppresses ferroptosis of induced pluripotent stem cells with ApoE4/E4 from a sporadic Alzheimer's disease patient. [PDF]
Wang Y +6 more
europepmc +1 more source
Homogenous Cell Transplantation Trials in Parkinson's Disease: A Systematic Review and Meta‐Analysis
Abstract Background The transplantation of homogenous cells has emerged as an investigational strategy for Parkinson's disease (PD), offering an alternative to symptomatic treatment. Objective We performed a systematic review and meta‐analysis to assess its clinical efficacy and safety.
Nolan Reinisch +4 more
wiley +1 more source
Correction: Discovery and optimization of tau targeted protein degraders enabled by patient induced pluripotent stem cells-derived neuronal models of tauopathy. [PDF]
Silva MC +9 more
europepmc +1 more source
Abstract Background Neurodegeneration with Brain Iron Accumulation (NBIA) is a heterogeneous group of heritable, mostly recessive, progressive neurodegenerative diseases characterized by iron deposition in the basal ganglia and brainstem. There are no solid global epidemiological data on prevalence and incidence of NBIA subtypes, but registry data and ...
Susanne A. Schneider +3 more
wiley +1 more source

