Results 211 to 220 of about 7,556,090 (298)

Integrated Multi-Omics Analysis Uncovers Molecular Dysregulation in Glucosylceramide Synthase-Deficient Human Induced Pluripotent Stem Cells. [PDF]

Mol Cell Proteomics
Beimdiek J, Cirksena K, Rossdam C, Brand-Merseburger S, Oberbeck A, Barbosa PV, Tzvetkova A, Juchem M, Bär C, Thum T, Schambach A, Pich A, Brügger B, Kuss AW, Buettner FFR.   +14 more
europepmc   +1 more source

The association between neural crest‐derived glia and melanocyte lineages throughout development and disease

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley   +1 more source

Engineering of functional auditory neurons from human induced pluripotent stem cells. [PDF]

Mil Med Res
Jeong M, Vattino LG, Djurisic M, Rose KP, Hyakusoku H, Spasic S, Ma XJ, Mohri H, Hertzano R, Takesian AE, Stankovic KM.   +10 more
europepmc   +1 more source

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

Developmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell, Tracy Eng, Jeffrey D. Amack, David Pruyne   +3 more
wiley   +1 more source

APOE4 Alters Early Transcriptional Programs and Inflammatory Signaling in Human Induced Pluripotent Stem Cells. [PDF]

Int J Mol Sci
Schulten W, Czaniera NJ, Fazel M, Kaltschmidt B, Kaltschmidt C.   +4 more
europepmc   +1 more source

Induced Pluripotent Stem Cell [PDF]

, 2020
openaire   +1 more source

Spatiotemporal cellular dynamics of the notochord shape intervertebral disc morphogenesis in the mouse embryo through apoptosis and proliferation

Developmental Dynamics, EarlyView.
Abstract Background The notochord is a midline structure essential for vertebrate embryogenesis, contributing to the development of the nervous system, digestive tract, and vertebral column. In particular, notochord signaling is indispensable for proper patterning and coordinated development of alternating vertebrae and intervertebral discs (IVDs ...
Julie Warin, Estelle Balissat, Pauline Colombier, Lily Paillat, Maeva Dutilleul, Anne Camus   +5 more
wiley   +1 more source

Correction: Patient induced pluripotent stem cells identify specificities of a reticular pseudodrusen phenotype in age-related macular degeneration. [PDF]

Genome Med
Hall JC, Sudhakar KK, Daniszewski M, Senabouth A, Abbott CJ, Liang HH, Kumar H, Lidgerwood GE, Mirzaei M, Ma JY, Atkeson T, Hirokawa Y, Nandrot EF, Barnett A, Cazevieille C, Manes G, Mountford S, Thompson P, Fletcher EL, Wu Z, Bahlo M, Ansell BRE, Paull D, Hewitt AW, Guymer RH, Powell JE, Pébay A.   +26 more
europepmc   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Differentiation of human induced pluripotent stem cells into cardiac valve cells using 2D and 3D differentiation protocols. [PDF]

Stem Cell Res Ther
Farzaneh Z, Brückner A, Fleischmann BK, Rieck S.   +3 more
europepmc   +1 more source