Review of articular cartilage repair techniques and their application in the horse
Abstract Articular cartilage lesions represent a significant career‐limiting problem in athletic horses. A healthy articular cartilage surface is vital for optimal joint function, and defects can result in irreversible degenerative changes. Successful treatment of cartilage lesions remains a long‐standing challenge for orthopaedic surgeons, prompting ...
Charlotte K. Barton +2 more
wiley +1 more source
Mitochondrial morphology in human fibroblasts and induced pluripotent stem cells in Leigh syndrome: A comparative analysis. [PDF]
Meshrkey F, Bakare AB, Rao RR, Iyer S.
europepmc +1 more source
Under‐Explored Species, Breeds and Cell Types With Potential for Cultivated Meat Production
This graphical abstract illustrates how the strategic selection of overlooked cell lines from novel species and specific agricultural breeds can help overcome current manufacturing bottlenecks in cultivated meat production. The schematic links the concept of an ‘ideal cell line’ to four key bioprocessing and product advantages that can be optimised ...
William Gordon‐Petrovskii +6 more
wiley +1 more source
Changes in Purine Metabolism During Differentiation of Dopamine Neurons from Human Induced Pluripotent Stem Cells. [PDF]
Grychowski L +7 more
europepmc +1 more source
Somatic cell reprogramming for Parkinson's disease treatment
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley +1 more source
Generation of human primordial germ cell-like cells from cumulus and blood cell-derived isogenic human induced pluripotent stem cells†. [PDF]
Llonch S +9 more
europepmc +1 more source
A 70‐year‐old man with recurrent cerebral infarctions, a subdural hematoma, and atherosclerotic disease involving multiple extracranial vascular territories was subsequently diagnosed with polycythemia vera (PV). In patients with recurrent cerebrovascular events accompanied by otherwise unexplained persistent erythrocytosis, JAK2 mutation testing and ...
Hui Zhao +5 more
wiley +1 more source
Navigating Human Astrocyte Differentiation: Direct and Rapid One-Step Differentiation of Induced Pluripotent Stem Cells to Functional Astrocytes Supporting Neuronal Network Development. [PDF]
Schuurmans IME +39 more
europepmc +1 more source
The Endothelial CXCR Family in Vascular Health and Disease
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu +4 more
wiley +1 more source
Induced pluripotent stem cells from sporadic pulmonary veno-occlusive disease exhibit altered endothelial commitment and stress-related transcriptional programs. [PDF]
Lian L +6 more
europepmc +1 more source

