Results 251 to 260 of about 8,076,620 (303)

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Changes in Purine Metabolism During Differentiation of Dopamine Neurons from Human Induced Pluripotent Stem Cells. [PDF]

Cell Mol Neurobiol
Grychowski L, Seifar F, Ozel E, Thite A, Sutcliffe DJ, Dinasarapu AR, Hess EJ, Jinnah HA.   +7 more
europepmc   +1 more source

Emerging Human‐Based Research Technologies for Investigating the Pathomechanisms and Therapies for Vascular Diseases

iNew Medicine, EarlyView.
ABSTRACT It is estimated that a large proportion of drug candidates fail in human clinical trials, mainly because animal models cannot fully replicate human disease and because of differential responses to various medications between humans and animals.
Weiping Ding, Iqra Ilyas, Suowen Xu
wiley   +1 more source

Pathways regulating the excitability of sympathetic neurons derived from human induced pluripotent stem cells

Fedele L, Maurer M, Tinker A, Andersson DA.   +3 more
europepmc   +1 more source

Retraction: Myogenic differentiation of VCP disease-induced pluripotent stem cells: A novel platform for drug discovery. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Generation of human primordial germ cell-like cells from cumulus and blood cell-derived isogenic human induced pluripotent stem cells†. [PDF]

Biol Reprod
Llonch S, Pinel L, Mattimoe T, Severino J, Zambelli F, Mallol A, Carvalho KF, Batlle-Morera L, Vassena R, Payer B.   +9 more
europepmc   +1 more source

Harnessing induced pluripotent stem cells and organoids for disease modeling and precision medicine. [PDF]

Stem Cell Res Ther
Lee CJ, Nam Y, Rim YA, Ju JH.
europepmc   +1 more source

Induced pluripotent stem cells from sporadic pulmonary veno-occlusive disease exhibit altered endothelial commitment and stress-related transcriptional programs. [PDF]

Front Cell Dev Biol
Lian L, Daniels N, Wanner N, Comhair S, Poplawski GHD, Asosingh K, Lopez-Gonzalez R.   +6 more
europepmc   +1 more source

Navigating Human Astrocyte Differentiation: Direct and Rapid One-Step Differentiation of Induced Pluripotent Stem Cells to Functional Astrocytes Supporting Neuronal Network Development. [PDF]

Glia
Schuurmans IME, Mordelt A, Guevara-Ferrer M, Linda K, Duineveld D, Puvogel S, Hommersom MP, Scheefhals N, Rahm L, Dyke E, Scholten GJ, Knorz C, Jimenez CG, van Egmond N, Oudakker A, Bijnagte-Schoenmaker C, van Bokhoven H, Wei W, Hofmann S, Jung-Klawitter S, Mojica-Perez S, Parent J, Carotenuto L, Weckhuysen S, Maas N, Elgersma Y, van de Ven E, Lefeber D, Lygeroudi A, de Vries HE, Jordi L, Polymenidou M, Mitchell-Garcia T, Dragan I, Dolga A, de Witte LD, van Karnebeek CDM, Ellis J, Garanto A, Nadif Kasri N.   +39 more
europepmc   +1 more source

Induced pluripotent stem cells from a transgenic minipig model of Huntington's disease reveal early metabolic changes. [PDF]

Dis Model Mech
Rysankova I, Sekac D, Hansikova H, Kepkova KV, Vodicka P, Vaskovicova M, Altmanova M, Juhas S, Juhasova J, Taborska E, Klempir J, Motlik J, Klima J, Eide L, Ellederova Z.   +14 more
europepmc   +1 more source