Results 251 to 260 of about 7,556,090 (298)

Precision Medicine in Neurodegeneration with Brain Iron Accumulation (NBIA) Disorders: An Update on Emerging Treatments

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Neurodegeneration with Brain Iron Accumulation (NBIA) is a heterogeneous group of heritable, mostly recessive, progressive neurodegenerative diseases characterized by iron deposition in the basal ganglia and brainstem. There are no solid global epidemiological data on prevalence and incidence of NBIA subtypes, but registry data and ...
Susanne A. Schneider, Divyani Garg, Vassilena Iankova, Thomas Klopstock   +3 more
wiley   +1 more source

Advances in the differentiation of induced pluripotent stem cells into vascular cells for the treatment of diabetic microvascular disease. [PDF]

Cardiovasc Diabetol
Wang S, Zhong H, Wu Y, Zhang Y, Sha A, Zhu Z, Fang X, Bao M, Sun D.   +8 more
europepmc   +1 more source

Correction: Generation of Human Melanocytes from Induced Pluripotent Stem Cells. [PDF]

PLoS One
Ohta S, Imaizumi Y, Okada Y, Akamatsu W, Kuwahara R, Ohyama M, Amagai M, Matsuzaki Y, Yamanaka S, Okano H, Kawakami Y.   +10 more
europepmc   +1 more source

Universal conditional knockout approach to multiple species, from fish to human induced pluripotent stem cells. [PDF]

Nucleic Acids Res
Choi JH, Moon J, Oh Y, Klompstra TM, Kim Y, Baek G, Kwak Y, Kim Y, Lee S, Park S, Ha J, Kwon O, Choi YK, Kim JH, Lee JH, Park J, Kim JK, Woo DH, Yoon KJ, Koo BK, Lee H.   +20 more
europepmc   +1 more source

Induced Pluripotent Stem Cells (iPSC) and Their Use in Disease Modeling. [PDF]

Cureus
Dorota A, Maryniak N, Mariankowska A, Milczarek C, Dorota M, Zywiec W, Kozlowski K, Koval I, Czyzewski B, Czyzewska J.   +9 more
europepmc   +1 more source

Generation of Friedreich's ataxia induced pluripotent stem cells carrying the FXN c.165 + 5G>C splicing mutation. [PDF]

Stem Cell Res
Yameogo P, Gerhart BJ, Sentmanat MF, Neilson A, Cui X, Verma M, Lynch DR, Napierala JS, Napierala M.   +8 more
europepmc   +1 more source

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Induced pluripotent stem cells

Russian Journal of Genetics, 2009
Induced pluripotent stem cells (iPS) result from a reprogramming of somatic cells via transduction with viral vectors expressing the Oct4, Sox2, c-Myc, Klf4, Nanog, and Lin28 genes, which are essential for the establishment and maintenance of the pluripotent state. In properties, iPS are almost fully similar to embryonic stem cells (ESC).
A I, Shevchenko, S P, Medvedev, N A, Mazurok, S M, Zakiian   +3 more
openaire   +2 more sources

Induced Pluripotent Stem Cells

2010
Reprogramming of mouse and human somatic cells into induced pluripotent stem (iPS) cells has been possible with retroviral expression of the pluripotency-associated transcription factors Oct4, Sox2, Nanog, and Lin28 as well as Klf4 and c-Myc. iPS cells hold great potential as a model for diseases from the perspective of the individual patient and as an
Zaehres, Holm, Kim, Jeong Beom, Scholer, Hans R.   +2 more
openaire   +9 more sources

Livestock Induced Pluripotent Stem Cells

Reproduction in Domestic Animals, 2012
ContentsChimeric animals generated from livestock‐induced pluripotent stem cells (iPSCs) have opened the door of opportunity to genetically manipulate species for the production of biomedical models, improving traits of agricultural importance and potentially providing a system to test novel iPSC therapies.
Y, Lu, J L, Mumaw, F D, West, S L, Stice
openaire   +2 more sources