Results 141 to 150 of about 12,028,372 (332)
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
, 1970 Potentiometer-type pressure transducer improves liquid level sensing by using the pressure-induced motion of a diaphragm to alter the resistance of the ...
Matica, S. W.
core +1 more source
Theory of the microwave induced zero resistance states in two-dimensional electron systems
, 2011 The phenomena of the microwave induced zero resistance states (MIZRS) and the microwave induced resistance oscillations (MIRO) were discovered in the ultraclean two-dimensional electron systems in 2001 -- 2003 and have attracted great interest of ...
A. P. Prudnikov +4 more
core +1 more source
The NALP3/NLRP3 Inflammasome Instigates Obesity-Induced Autoinflammation and Insulin Resistance
Nature Medicine, 2010 The emergence of chronic inflammation during obesity in the absence of overt infection or well-defined autoimmune processes is a puzzling phenomenon. The Nod-like receptor (NLR) family of innate immune cell sensors, such as the nucleotide-binding domain,
B. Vandanmagsar +8 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Modes of action of non-pathogenic strains of Fusarium oxysporum in controlling Fusarium wilts
Plant Protection Science, 2002 Many studies have demonstrated the capacity of non-pathogenic strains of F. oxysporum to control Fusarium diseases.These non-pathogenic strains show several modes of action contributing to their biocontrol capacity.
C. Alabouvette, Ch. Olivain
doaj +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
, 2011 We report on theoretical studies of recently discovered microwave-induced resistance oscillations and zero resistance states in Hall bars with two occupied subbands.
B. K. Ridley +5 more
core +1 more source
Cancers, 2011 Platinum complexes are clinically used as adjuvant therapy of cancers aiming to induce tumor cell death. Depending on cell type and concentration, cisplatin induces cytotoxicity, e.g., by interference with transcription and/or DNA replication mechanisms.
A. Florea, Dietrich Büsselberg
semanticscholar +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source