Results 221 to 230 of about 12,028,372 (332)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Cutting the defense budget: How allocation costs shape induced resistance in plants. [PDF]
Bass E.
europepmc +1 more source
Bringing Fundamental Insights of Induced Resistance to Agricultural Management of Herbivore Pests. [PDF]
Poelman EH +10 more
europepmc +1 more source
When Do Antibiotics Induce “Resistance”? [PDF]
openaire +2 more sources
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
Corrigendum: QTL for induced resistance against leaf rust in barley. [PDF]
Matros A, Schikora A, Ordon F, Wehner G.
europepmc +1 more source
Physiological and biochemical characterization of biochar-induced resistance against bacterial wilt of eggplants. [PDF]
Ahmad CA, Haider MS, Akhter A.
europepmc +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Mechanisms of induced resistance to the antitumoral agent ZZW-115 in pancreas ductal adenocarcinoma. [PDF]
Santofimia-Castaño P +8 more
europepmc +1 more source

