Results 71 to 80 of about 12,028,372 (332)

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

TRAIL-induced variation of cell signaling states provides nonheritable resistance to apoptosis. [PDF]

open access: yes, 2019
TNFα-related apoptosis-inducing ligand (TRAIL), specifically initiates programmed cell death, but often fails to eradicate all cells, making it an ineffective therapy for cancer.
Baskar, Reema   +8 more
core  

Signatures of pressure induced superconductivity in insulating Bi2212

open access: yes, 2010
We have performed several high pressure electrical resistance experiments on Bi1.98Sr2.06Y0.68Cu2O8, an insulating parent compound of the high-Tc Bi2212 family of copper oxide superconductors.
Cuk, T.   +6 more
core   +1 more source

Theory of the fractional microwave-induced resistance oscillations [PDF]

open access: yes, 2007
We develop a systematic theory of microwave-induced oscillations in magnetoresistivity of a 2D electron gas in the vicinity of fractional harmonics of the cyclotron resonance, observed in recent experiments.
A. D. Mirlin   +3 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Proteomic responses of fruits to environmental stresses

open access: yesFrontiers in Plant Science, 2013
Fruits and vegetables are extremely susceptible to decay and easily lose commercial value after harvest. Different strategies have been developed to control postharvest decay and prevent quality deterioration during postharvest storage, including cold ...
Zhulong eChan
doaj   +1 more source

Lipid-induced hepatic insulin resistance

open access: yesAging, 2013
The principal function of insulin in the liver is to suppress glucose production when blood glucose concentrations increase. This process is impaired in hepatic insulin resistance and contributes to postprandial hyperglycemia. The development of hepatic insulin resistance is very closely linked to non alcoholic fatty liver disease (NAFLD), and is a ...
Thomas, Galbo, Gerald I, Shulman
openaire   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Mass Spectrometry Imaging to map metabolites in plant-microbe interactions: grapevine as a case study

open access: yesOENO One
Every year, viticulture faces several disease outbreaks caused by pathogens with different life cycles and modes of action, and due to climate changes, the appearance of new pathogens is a concern for viticulture.
Marisa Maia   +4 more
doaj   +1 more source

A complex protein derivative acts as biogenic elicitor of grapevine resistance against powdery mildew under field conditions

open access: yesFrontiers in Plant Science, 2015
Powdery mildew caused by Erysiphe necator is one of the most important grapevine diseases in several viticulture areas, and high fungicide input is required to control it. However, numerous synthetic chemical pesticides are under scrutiny due to concerns
Andrea eNesler   +5 more
doaj   +1 more source

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