Results 61 to 70 of about 7,682,818 (299)

The Chemistry of Plant–Microbe Interactions in the Rhizosphere and the Potential for Metabolomics to Reveal Signaling Related to Defense Priming and Induced Systemic Resistance

Frontiers in Plant Science, 2018
Plant roots communicate with microbes in a sophisticated manner through chemical communication within the rhizosphere, thereby leading to biofilm formation of beneficial microbes and, in the case of plant growth-promoting rhizomicrobes/-bacteria (PGPR ...
Msizi I. Mhlongo, Lizelle A. Piater, Ntakadzeni E. Madala, Nico Labuschagne, Ian A. Dubery   +4 more
doaj   +1 more source

Reduced susceptibility to eccentric exercise-induced muscle damage in resistance-trained men is not linked to resistance training-related neural adaptations [PDF]

, 2015
The purpose of this study was to examine the acute effects of maximal concentric vs. eccentric exercise on the isometric strength of the elbow flexor, as well as the biceps brachii muscle electromyographic (EMG) responses in resistance-trained (RT) vs ...
TW Beck, X Ye, NP Wages
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Induced Systemic Resistance and the Rhizosphere Microbiome [PDF]

The Plant Pathology Journal, 2013
Microbial communities that are associated with plant roots are highly diverse and harbor tens of thousands of species. This so-called microbiome controls plant health through several mechanisms including the suppression of infectious diseases, which is especially prominent in disease suppressive soils.
Bakker, P.A.H.M., Doornbos, R.F., Zamioudis, C., Berendsen, R.L. and Pieterse, C.M.J. (   +8 more
openaire   +4 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Abscisic Acid as a Dominant Signal in Tomato During Salt Stress Predisposition to Phytophthora Root and Crown Rot

Frontiers in Plant Science, 2018
Salt stress predisposes plants to Phytophthora root and crown rot in an abscisic acid (ABA)-dependent manner. We used the tomato–Phytophthora capsici interaction to examine zoospore chemoattraction and assessed expression of pathogenesis-related (PR ...
Matthew F. Pye, Sara M. Dye, Renata Sousa Resende, James D. MacDonald, Richard M. Bostock   +4 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synthetic Mono-Rhamnolipids Display Direct Antifungal Effects and Trigger an Innate Immune Response in Tomato against Botrytis Cinerea

Molecules, 2020
Natural rhamnolipids are potential biocontrol agents for plant protection against bacterial and fungal diseases. In this work, we synthetized new synthetic mono-rhamnolipids (smRLs) consisting in a rhamnose connected to a simple acyl chain and differing ...
Mathilde Robineau, Sarah Le Guenic, Lisa Sanchez, Ludovic Chaveriat, Vincent Lequart, Nicolas Joly, Maryline Calonne, Cédric Jacquard, Stéphane Declerck, Patrick Martin, Stephan Dorey, Essaid Ait Barka   +11 more
doaj   +1 more source

Immunotherapy Resistance by Inflammation-Induced Dedifferentiation [PDF]

Cancer Discovery, 2018
Abstract A promising arsenal of targeted and immunotherapy treatments for metastatic melanoma has emerged over the last decade. With these therapies, we now face new mechanisms of tumor-acquired resistance. We report here a patient whose metastatic melanoma underwent dedifferentiation as a resistance mechanism to adoptive T-cell ...
Arnav Mehta, Yeon Joo Kim, Lidia Robert, Jennifer Tsoi, Begoña Comin-Anduix, Beata Berent-Maoz, Alistair J. Cochran, James S. Economou, Paul C. Tumeh, Cristina Puig-Saus, Antoni Ribas   +10 more
openaire   +4 more sources

Development of resistance towards artesunate in MDA-MB-231 human breast cancer cells. [PDF]

, 2011
Breast cancer is the most common cancer and the second leading cause of cancer death in industrialized countries. Systemic treatment of breast cancer is effective at the beginning of therapy.
Ulrich Pfeffer, Killian, Peter H., Fichtner Iduna, Efferth, Thomas, Iduna Fichtner, Pfeffer Ulrich, Pfeffer, U., Emanuel Kronski, Bachmeier Beatrice, Killian, P.H., Fichtner, I., Beatrice Bachmeier, Bachmeier, B., Thomas Efferth, Kronski, Emanuel, Efferth Thomas, Kronski, E., Pfeffer, Ulrich, Fichtner, Iduna, Bachmeier, Beatrice, Peter H. Killian, Peter H Killian, Efferth, T., Kronski Emanuel, Killian Peter H.   +24 more
core   +1 more source