Results 101 to 110 of about 86,483 (258)

Correlation of Clinical Symptoms and Sputum Inflammatory Markers with Air Pollutants in Stable COPD Patients in Beijing Area

International Journal of COPD, 2020
Chenxia Guo, Xiaoyan Sun, Wenqi Diao, Ning Shen,* Bei He* Department of Respiratory Medicine, Peking University Third Hospital, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Bei HePeking ...
Guo C, Sun X, Diao W, Shen N, He B
doaj  

Sputum–plasma ratio of soluble receptor for advanced glycation end-products in patients with chronic obstructive pulmonary disease

Egyptian Journal of Chest Disease and Tuberculosis, 2016
Background: Chronic obstructive pulmonary disease (COPD) is associated with systemic inflammatory consequences. Receptor for advanced glycation end products (RAGE) acts as an important progression factor amplifying the immune and inflammatory responses ...
Essam Gouda Hassanein, Anwar Ahmad ElGanady, Ayman Ibrahim Baess, Yasmine Amr Issa, Essam Mohamed ElAkhtel   +4 more
doaj   +1 more source

Nevirapine versus Efavirenz for patients co-infected with HIV and Tuberculosis: A Randomised Non-Inferiority Trial [PDF]

, 2013
BACKGROUND: In countries with a high incidence of HIV and tuberculosis co-infection, nevirapine and efavirenz are widely used as antiretroviral therapy but both interact with antituberculosis drugs. We aimed to compare efficacy and safety of a nevirapine-
Agnès Sobry, Alexandra Calmy, Anne-Marie Taburet, Avihingsanon, Blackwelder, Boulle, Carlota Silva, Chen, Christine Rouzioux, Christophe Michon, Cohen, Cohen, Davies, Dejesus, Dieterich, Elisabeth Baudin, Elizabete Nunes, Flandre, Ford, Gengiah, Gulick, Ilesh Jani, Kwara, Laura Ciaffi, Maartens, Manosuthi, Manosuthi, Maryline Bonnet, Matteelli, Mbuagbaw, Meintjes, Nilesh Bhatt, Rui Bastos, Scourfield, Shipton, Soriano, Swaminathan, Tang, Telenti, van Leth   +39 more
core   +3 more sources

Targeting Immunologic Pathways in Eosinophilic Granulomatosis With Polyangiitis: Translating Emerging Evidence Into Clinical Practice

Allergy, EarlyView.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh, Lior Seluk, Philipp Bosch, Carolina Aguiar, Jens Thiel, Bernhard Hellmich, Michael E. Wechsler, Salman Siddiqui   +7 more
wiley   +1 more source

A phase II study on safety and efficacy of high-dose N-acetylcysteine in patients with cystic fibrosis

European Journal of Medical Research, 2009
Objective We conducted a single-centre, randomised, double-blinded, placebo-controlled phase II clinical study to test safety and efficacy of a 12-week therapy with low-dose (700 mg/daily) or high-dose (2800 mg/daily) of NAC. Methods Twenty-one patients (
Dauletbaev N, Fischer P, Aulbach B, Gross J, Kusche W, Thyroff-Friesinger U, Wagner TOF, Bargon J   +7 more
doaj   +1 more source

臨床所見および検査成績からのスコアーによる喘息分類の特徴 [PDF]

, 1992
Twenty six patients with bronchial asthma was classified by clinical symptoms and singns (clinical diagnosis), and the classification by clinical diagnosis was compared with the classification by a score calculated from clinical findings and examinations
Honke, Naoko, Kimura, Ikuro, Kitani, Hikaru, Kusaura, Yasuhiro, Mifune, Takashi, Mitsunobu, Fumihiro, Okazaki, Morihiro, Okuda, Hiroyuki, Takatori, Akimasa, Tanimizu, Masakuni, Tanizaki, Yoshiro   +10 more
core   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

Small Airways Dysfunction and Remission in Adults With Asthma: A Longitudinal Exploratory Analysis of the AssessmenT of smalL Airways involvemeNT In aSthma (ATLANTIS) Study

Allergy, EarlyView.
We conducted a post hoc analysis of ATLANTIS, a multinational prospective study including 684 adults with asthma. Fewer small airway symptoms and lower disease activity are independently associated with asthma remission. Replicated airway transcriptomic signatures show increased IL‐4/13 signalling and reduced coagulation pathways across the ATLANTIS ...
Akshi Kumar, Rory Chan, Nazanin Zounemat‐Kermani, Eleanor Quek, Ian M. Adcock, Bianca Beghe, Christopher Brightling, Dave Singh, Janwillem Kocks, Alberto Papi, Klaus F. Rabe, Ulrica Scaffidi‐Argentina, Maarten van den Berge, Monica Kraft, Salman Siddiqui   +14 more
wiley   +1 more source

Lipid-laden alveolar macrophages in induced sputum in patients with gastroesophageal reflux disease

Бюллетень сибирской медицины, 2006
The aim of the study was to evaluate the diagnostic role of a lipid index of macrophages in induced sputum as a marker of aspiration of acidic gastric contents.
L. I. Volkova, O. A. Anichkina, I. V. Sukhodolo, R. I. Pleshko, V. S. Bogomyagkov   +4 more
doaj   +1 more source

Antimicrobial peptides in induced sputum

, 2006
COPD is a severe illness concerning airways. We tried to find out whether inflammation already exists in the airways of young healthy smokers and compared the results with those of young healthy non-smokers.
openaire   +3 more sources