Seropositive Rheumatoid Arthritis Emerging During Acute Phase of Lung Abscess: A Case Report
We report a rare case of seropositive rheumatoid arthritis (RA) that became clinically apparent during the acute phase of lung infection. This case demonstrates that RA can be diagnosed during the acute course of a respiratory infection and highlights the diagnostic value of rheumatoid factor and anti‐citrullinated protein antibodies testing when new ...
Yusuke Arai +5 more
wiley +1 more source
Diagnostic stewardship aiming at expectorated or induced sputum promotes microbial diagnosis in community-acquired pneumonia. [PDF]
Waagsbø B +12 more
europepmc +1 more source
This study investigated airway epithelial barrier dysfunction persistence in ex‐smokers with COPD and underlying mechanisms using single‐cell RNA and ATAC sequencing. Epigenetic NKX2‐1/SPDEF dysregulation maintains goblet cell hyperplasia and barrier dysfunction despite long‐term smoking cessation.
Ayaka Shiota +17 more
wiley +1 more source
Erratum: Characteristics of Induced-Sputum Inflammatory Phenotypes in Adults with Asthma: Predictors of Bronchial Eosinophilia [Corrigendum]. [PDF]
europepmc +1 more source
AI‐Enabled Imaging for Pathogen Detection Under Stress Conditions: A Systematic Review
ABSTRACT Advances in pathogen detection that incorporate artificial intelligence (AI) may capture microbial signals under challenging environmental conditions that traditional methods miss. This systematic review evaluates the application, performance, and methodological characteristics of AI‐enabled imaging for pathogen detection, including its impact
MeiLi Papa +3 more
wiley +1 more source
Fractional exhaled nitric oxide and eosinophil count in induced sputum to guide the management of children with asthma: a cost-utility analysis. [PDF]
Buendía JA +2 more
europepmc +1 more source
‘The Hero's journey’: Narratives on the transition to motherhood with cystic fibrosis
Abstract Objectives This study aimed to explore the impact of cystic fibrosis (CF) on the transition to motherhood using a strength‐based narrative approach. It sought to elevate the voices of women with CF and examine how they navigate pregnancy and early motherhood in the context of chronic illness. Design A qualitative narrative study was conducted,
Alena J. Haines +3 more
wiley +1 more source
Matrix metalloproteinases levels in induced sputum in IPF and CTD-ILD. [PDF]
Zhang F +10 more
europepmc +1 more source
Inflammatory profile of induced sputum composition in systemic sclerosis and comparison with healthy volunteers. [PDF]
Jacquerie P +8 more
europepmc +1 more source
Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos +16 more
wiley +1 more source

