Results 51 to 60 of about 262,962 (308)

Outcome of adult T-lymphoblastic lymphoma after acute lymphoblastic leukemia-type treatment: a GOELAMS trial

Haematologica, 2007
Background and Objectives T-lymphoblastic lymphoma is an infrequent disease usually treated as T-acute lymphoblastic leukemia with an induction chemotherapy course and sequential reinduction and maintenance chemotherapy.
Mathilde Hunault, Malgorzata Truchan-Graczyk, Denis Caillot, Jean-Luc Harousseau, Serge Bologna, Chantal Himberlin, Denis Guyotat, Christian Berthou, Philippe Casassus, Laurence Baranger, Marie-Christine Béné, Norbert Ifrah, Emmanuel Gyan   +12 more
doaj   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

Role of Intracellular Drug Disposition in the Response of Acute Myeloid Leukemia to Cytarabine and Idarubicin Induction Chemotherapy

, 2023
Despite its often low efficacy and high toxicity, the standard treatment for acute myeloid leukemia (AML) is induction chemotherapy with cytarabine and idarubicin.
Martínez Laperche, Carolina, Chillón, María C, Martínez Arranz, Ibon, Buño Borde, Ismael, María C. Chillón, Marcos González-Díaz, Oscar Briz, Ibon Martínez-Arranz, Jose J. G. Marin, Cives-Losada, Candela, Cives Losada, Candela, Díez Martín, José Luis, Briz, Oscar, Rocio I. R. Macias, González Díaz, Marcos, Rodríguez Macías, Gabriela, Ismael Buño, José L. Díez-Martín, González-Díaz, Marcos, Carolina Martínez-Laperche, Marin, Jose J G, Martínez-Laperche, Carolina, Macias, Rocio I R, Gabriela Rodríguez-Macías, Martínez-Arranz, Ibon, Marin, Jose J. G., Candela Cives-Losada, Chillón, María, Buño, Ismael, Díez-Martín, José L, Macias, Rocio I. R., Rodríguez-Macías, Gabriela   +31 more
core   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Immunomodulated anterior chemotherapy followed by concurrent chemoradiotherapy in locally advanced tongue cancer: An Institutional experience

Indian Journal of Medical and Paediatric Oncology, 2015
Context: Sequential induction chemotherapy with cisplatin and 5-fluorouracil (PF) along with interferon-alpha2b and concurrent chemoradiation offers superior loco-regional control for locally advanced carcinoma of oral tongue.
Bappaditya Chhatui, Devleena, Sanjoy Roy, Tapas Maji, Debarshi Lahiri, Jaydip Biswas   +5 more
doaj   +1 more source

Low-dose fractionated radiation with induction docetaxel and cisplatin followed by concurrent cisplatin and radiation therapy in locally advanced nasopharyngeal cancer: A randomized phase II–III trial

Hematology/Oncology and Stem Cell Therapy, 2021
Objective/Background: To evaluate the efficacy and outcome of adding low-dose fractionated radiotherapy (LDFRT) to induction chemotherapy plus concurrent chemoradiation in locally advanced nasopharyngeal carcinoma (LANPC).
Nasser M. Al-Rajhi, Ehab M. Khalil, Shoaib Ahmad, Hussein Soudy, Mohammad AlGhazi, Doha M. Fatani, Muhammed Memon, Moheieldin Abouzied, Yasser M. Khafaga   +8 more
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Key environmental stress biomarker candidates for the optimisation of chemotherapy treatment of leukaemia [PDF]

, 2014
The impact of fluctuations of environmental parameters such as oxygen and starvation on the evolution of leukaemia is analysed in the current review.
Pefani, Eleni, Pistikopoulos, Efstratios N., Brito Dos Santos, Susana, Misener, Ruth, Mantalaris, Athanasios, Velliou, Eirini G., Panoskaltsis, Nicki, Fuentes-Garí, Maria   +7 more
core   +1 more source

Induction Chemotherapy for Locally Advanced Esophageal Cancer

Journal of Gastrointestinal Cancer, 2018
Concurrent chemoradiotherapy followed by surgery is the standard treatment for locally advanced esophageal cancer (EC), and the role of induction chemotherapy (IC) remains unclear. We aimed to study if the addition of IC to standard treatment increases the rate of pathologic complete response (pCR).We assembled a retrospective analysis of patients (pts)
Guilherme Harada, Renata Rodrigues da Cunha Colombo Bonadio, Frederico Cantarino Cordeiro de Araújo, Carolina Ribeiro Victor, Rubens Antonio Aissar Sallum, Ulysses Ribeiro Junior, Ivan Cecconello, Flávio Roberto Takeda, Tiago Biachi de Castria   +8 more
openaire   +2 more sources

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source