Results 111 to 120 of about 1,722,169 (314)
An Empirical Exploration on the Supervision of PhD Students Closely Collaborating with Industry [PDF]
With an increase of PhD students working in industry, there is a need to understand what factors are influencing supervision for industrial students. This paper aims at exploring the challenges and good approaches to supervision of industrial PhD students.
arxiv
Clinical significance of stratifying prostate cancer patients through specific circulating genes
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian+12 more
wiley +1 more source
Multi-Industry Simplex 2.0 : Temporally-Evolving Probabilistic Industry Classification [PDF]
Accurate industry classification is critical for many areas of portfolio management, yet the traditional single-industry framework of the Global Industry Classification Standard (GICS) struggles to comprehensively represent risk for highly diversified multi-sector conglomerates like Amazon.
arxiv
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita+1 more
wiley +1 more source
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi+5 more
wiley +1 more source
The Control of Industrial Bladder Tumours: A Code of Working Practice Recommended by the British Dyestuffs Industry for the Manufacture and Use of Products Causing Tumours of the Bladder [PDF]
T. S. Scott, M. H. C. Williams
openalex +1 more source
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric+11 more
wiley +1 more source
Handbook of the Daily News Sweated Industries' Exhibition, May 1906 [PDF]
Richard Mudie-Smith
openalex +1 more source