Results 51 to 60 of about 1,064,410 (251)

INTERNATIONAL MARKET ORIENTATION FOCUSING FACTORS, THEIR POWER AND SIGNIFICANCE [PDF]

open access: yesZbornik Radova Ekonomskog Fakulteta u Istočnom Sarajevu, 2011
A new approach to solvingeconomic problems in the Republic of Srpska, inrelation to current practice, should includesignificant changes in the way of doing business byenterprises and entrepreneurs.
Vedran Stanetić
doaj  

Research on Reducing Regional Outage Loss Based on Entropy Weight-Gray Correlation Analysis

open access: yesZhongguo dianli, 2020
Outage loss is one of the indicators to measure the economics of the power grid. Reasonable estimation of outage loss can provide a basis for improving distribution network reliability, social emergency power distribution, and public preventive budget ...
Jun HAN   +5 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

L’enseignement technique à l’écran. Modernité technique et propagande cinématographique dans un film documentaire de 1930

open access: yesImages du Travail, Travail des Images, 2020
In order to understand what technical and vocational education meant in France in the 1920s and 1930s, this article analyses a documentary film on écoles nationales professionnelles in 1930.
Stéphane Lembré
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Designing a Model for Predicting Valuation of Block Trade Transactions with a Focus on GRU Artificial Neural Network in the Industry [PDF]

open access: yesراهبرد مدیریت مالی
Predicting the valuation of blockTrade transaction allows the market to evaluate control over companies in an efficient manner.In this research, by measuring the indicators affecting block transactions in three active industries in Tehran Stock Exchange ...
Adeleh Bahreini   +2 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

TECNOLOGIA DA INFORMAÇÃO E PRODUTIVIDADE NA INDÚSTRIA BRASILEIRA

open access: yesRAE: Revista de Administração de Empresas, 2009
The article seeks to quantify the impact of information technology solutions on workers' productivity in the Brazilian processing industry. This study was based on a sample of 26,776 companies. This data was obtained from the Annual Industrial Study (PIA)
Jano Moreira de Souza   +5 more
doaj  

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