Results 71 to 80 of about 1,722,169 (314)

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

ESTIMATION OF THE INNOVATIVE PROJECTS INVESTMENT POTENTIAL AT THE MACHINE BUILDERS (EVIDENCE FROM LLC "TURBOMASH")

open access: yesBaltic Journal of Economic Studies, 2015
The object of the article is to investigate methodic approach to modeling and formalized estimation of the innovative projects investment potential at the machine builders at different stages of innovative cycle. Methodology.
Sergii Illiashenko, Oleg Olefirenko
doaj  

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

Marine Gelatine from Rest Raw Materials

open access: yesApplied Sciences, 2018
In recent years, demand for consumption of marine foods, and especially fish, has substantially increased worldwide. The majority of collagen available is sourced from mammalian-derived products.
Ivan Milovanovic, Maria Hayes
doaj   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

open access: yesMolecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang   +8 more
wiley   +1 more source

Chief Development Tendencies, Structural Changes and Innovativeness of the Industrial and Service Sectors in Poland

open access: yesQuaestiones Geographicae, 2016
The goal of this article is to determine regularities concerning structural changes in the industrial and service sectors in Poland in the light of trends observable in the development of the world and national economies.
Dominiak Joanna, Rachwał Tomasz
doaj   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

A holistic look at requirements engineering practices in the gaming industry [PDF]

open access: yesarXiv, 2018
In this work we present an account of the status of requirements engineering in the gaming industry. Recent papers in the area were surveyed. Characterizations of the gaming industry were deliberated upon by portraying its relations with the market industry.
arxiv  

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

open access: yesMolecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang   +10 more
wiley   +1 more source

ISLAMIC MICROFINANCE: LOCOMOTIVE IN THE SERVICE OF FINANCIAL INCLUSION

open access: yesEuropean Journal of Islamic Finance, 2017
The exclusion of poor people within the society from the conventional banking system was the starting and focal point for the creation and development of microfinance institutions.
SALMA DRISSI
doaj   +1 more source

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