Results 41 to 50 of about 28,590 (257)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

LSEWOA: An Enhanced Whale Optimization Algorithm with Multi-Strategy for Numerical and Engineering Design Optimization Problems

Sensors
The Whale Optimization Algorithm (WOA) is a bio-inspired metaheuristic algorithm known for its simple structure and ease of implementation. However, WOA suffers from issues such as premature convergence, low population diversity in the later stages of ...
Junhao Wei, Yanzhao Gu, Yuzheng Yan, Zikun Li, Baili Lu, Shirou Pan, Ngai Cheong   +6 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Path Planning Optimization of Smart Vehicle With Fast Converging Distance-Dependent PSO Algorithm

IEEE Open Journal of Intelligent Transportation Systems
Path planning is a crucial technology and challenge in various fields, including robotics, autonomous systems, and intelligent transportation systems.
Muhammad Haris, Haewoon Nam
doaj   +1 more source

Multi-objective reservoir operation using particle swarm optimization with adaptive random inertia weights

Water Science and Engineering, 2020
Based on conventional particle swarm optimization (PSO), this paper presents an efficient and reliable heuristic approach using PSO with an adaptive random inertia weight (ARIW) strategy, referred to as the ARIW-PSO algorithm, to build a multi-objective ...
Hai-tao Chen, Wen-chuan Wang, Xiao-nan Chen, Lin Qiu   +3 more
doaj   +1 more source

Hyperbolic Tangent - Based Adaptive Inertia Weight Particle Swarm Optimization

Jurnal Nasional Teknik Elektro, 2023
This paper presents a study on using adaptive inertia weight (AIW) in particle swarm optimization (PSO) for solving optimization problems. An AIW function based on the hyperbolic tangent function was proposed, with the function parameters adaptively ...
Yaw Opoku Mensah Sekyere, Francis Boafo Effah, Philip Yaw Okyere   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

A New Data Processing Approach for the SHPB Test Based on PSO-TWER

Applied Sciences
This study addresses the challenge of accurately determining the arrival time of stress wave signals in SHPB test data processing. To eliminate human error, we introduce the time-window energy ratio method and evaluate six filters for noise reduction ...
Xuesong Wang, Zhenyang Xu, Lianjun Guo
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

MPC-Based Virtual Energy Storage System Using PV and Air Conditioner to Emulate Virtual Inertia and Frequency Regulation of the Low-Inertia Microgrid

IEEE Access, 2022
Grid-connected large-scale power converter-based intermittent renewable energy sources (RES) reduce system inertia, increase frequency fluctuation, and increase the rate of change of frequency (RoCoF).
Jonglak Pahasa, Potejanasak Potejana, Issarachai Ngamroo   +2 more
doaj   +1 more source