Results 21 to 30 of about 2,520 (189)

First case of infant botulism in Sicily—case report [PDF]

Italian Journal of Pediatrics
Background Botulism is a rare and life-threatening disease caused by the potent botulinum neurotoxin (BoNT), which can be produced by Clostridium botulinum (C. botulinum) and related bacteria.
Antonino Fazzino, Carmelinda Cavallaro, Francesca Cavataio, Giulia Linares, Antonina Lo Cascio, Carla Lo Porto, Giuseppe Santangelo, Laura Venuti, Giovanni Corsello, Claudia Colomba   +9 more
doaj   +2 more sources

Infant botulism in Singapore. [PDF]

Singapore Med J, 2020
Charan N, Wong JJ, Chan WSD, Ho ZJM, Sim HCJ, Loh JP, Foo LY, Octavia S, Ang M, Thoon KC.   +9 more
europepmc   +4 more sources

The unsung hero: ntnh gene as complementary botulism marker [PDF]

Frontiers in Cellular and Infection Microbiology
Botulism is a rare but severe neurological disease caused by botulinum neurotoxins (BoNTs). Standard diagnostic methods including the mouse bioassay (SMB) and bont gene type-specific PCR, are often limited by the high genetic diversity among bont ...
Sylvia Valdezate, Mónica Valiente, Sergio Díaz-Ramón, Gema Carrasco, María J. Medina-Pascual, Javier Pardos, María Isabel Hurtado, Noelia Garrido, Pilar Villalón, Antonio J. Martín-Galiano   +9 more
doaj   +2 more sources

Infant Botulism: A Case Study in Integrated Clinical and Public Health Response. [PDF]

Clin Case Rep
ABSTRACT Early recognition of constipation, feeding difficulty, and descending weakness in infants is vital for prompt diagnosis of infant botulism. Bedside nerve studies support early treatment. Rapid public health notification and coordinated access to specific therapies, including timely use of BAT and BIG‐IV, are essential to optimize outcomes and ...
Gannon J, Fallon Verbruggen T, Burke S, Loughlin L, Brits C, Tedford K, McHugh JC, Mayberry H, O'Regan M, Freyne B, Conroy N.   +10 more
europepmc   +2 more sources

First confirmed case of infant botulism in Africa, caused by a dual-toxin-producing Clostridium botulinum strain

International Journal of Infectious Diseases, 2021
Botulism, a rare life-threatening toxemia, is probably underdiagnosed in all of its forms in Africa. This study reports the first laboratory-supported case of infant botulism on the African continent.
Marné N. Vosloo, Christoffel J. Opperman, Hermanus D.W. Geyer, Grace M. Setshedi, Mushal Allam, Stanford Kwenda, Arshad Ismail, Zamantungwa T.H. Khumalo, Adrian J. Brink, John A. Frean, Jennifer Rossouw   +10 more
doaj   +1 more source

Infant Botulism: a network to improve the diagnosis and treatment of a rare and under-diagnosed disease

Emergency Care Journal, 2008
Infant Botulism is a form of human botulism in which ingested spores of Clostridium botulinum germinate, colonize the infant’s colon, in which they produce botulinum neurotoxin.
Davide Lonati, Carlo Locatelli, Stefania Bigi, Sarah Vecchio, Valeria Petrolini, Andrea Giampreti, Lucia Fenicia, Dario De Medici, Luigi Manzo   +8 more
doaj   +1 more source

Antimicrobial Susceptibility of 260 Clostridium botulinum Type A, B, Ba, and Bf Strains and a Neurotoxigenic Clostridium baratii Type F Strain Isolated from California Infant Botulism Patients [PDF]

Antimicrobial Agents and Chemotherapy, 2018
Jason R Barash
exaly   +2 more sources

Infant botulism [PDF]

Journal of Perinatology, 2007
Infant botulism results from the absorption of heat-labile neurotoxin produced in situ by ingested Clostridium botulinum. Honey and environmental exposure are the main sources of acquisition of the organism. Clinical manifestations are owing to progressive neuromuscular blockade, initially of muscles innervated by cranial nerves and later of the trunk,
  +5 more sources

Exploring the genetic background of the botulism neurotoxin BoNT/B2 in Spain

Microbiology Spectrum, 2023
To determine whether the neurotoxin BoNT/B2 causing botulism in Spain is clonal, the genetic diversity and phylogenetic relationships of Clostridium botulinum from food-borne episodes and infant cases of the condition were explored.
Sylvia Valdezate, Gema Carrasco, María J. Medina, Noelia Garrido, Silvia del Pino, Monica Valiente, María P. Pallarés, Pilar Villalon   +7 more
doaj   +1 more source

Adult Intestinal Toxemia Botulism

Toxins, 2020
Intoxication with botulinum neurotoxin can occur through various routes. Foodborne botulism results after consumption of food in which botulinum neurotoxin-producing clostridia (i.e., Clostridium botulinum or strains of Clostridium butyricum type E or ...
Richard A. Harris, Fabrizio Anniballi, John W. Austin   +2 more
doaj   +1 more source