Results 31 to 40 of about 299,566 (148)

Pragmatic Phenotype–Electrophysiology–Genomics Integration in Pediatric Congenital Myasthenic Syndromes: Insights From 36 Patients in a Single‐Center Study in China

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
In 36 Chinese pediatric CMS patients, integrated phenotype, RNS, and genomic assessment revealed marked genetic heterogeneity across 17 CMS‐associated genes and frequent VUS‐related uncertainty. Genotype‐informed therapy improved MG‐ADL scores, while CHAT‐CMS identified a high‐risk subgroup for early respiratory failure and mortality.
Liya Cui, Kaiyue Ma, Xiaona Fu, Lin Ge, Bingbing Jia, Wenna Ma, Lei Yang, Zhimei Liu, Junlan Lv, Wenmiao Xu, Lijuan Wang, Guangyuan Zhao, Jiuwei Li, Jie Wu, Quan Wang, Changhong Ding, Xiaotun Ren, Xinming Shen, Hui Xiong   +18 more
wiley   +1 more source

Peanut butter confirmed as the source in a case of infant botulism, United Kingdom, 2024

Eurosurveillance
A 6-month-old infant was hospitalised with suspected infant botulism after being given peanut butter to reduce their risk of developing peanut allergy.
Gauri Godbole
doaj   +1 more source

Feasibility and Safety of Washed Microbiota Transplantation as Salvage Therapy for Refractory Non‐CDI Gut Pathogens in Critically Ill Patients

Microbial Biotechnology, Volume 19, Issue 8, August 2026.
Ten patients with definite gut infection evidence beyond CDI underwent 29 WMT infusions. 50% (5/10) of patients obtained clinical cure after WMT. 20% (2/10) of patients achieved clinical improvement and 30% (3/10) showed no response 7 days after WMT. One transient WMT‐related fever occurred (1/29, 3.45%).
Jie Xu, Aoli Diao, Rujun Ai, Xia Wu, Quan Wen, Yuyan Xiao, Xinyi He, You Yu, Zulun Zhang, Yeqing Wang, Zhihua Zhang, Faming Zhang, Bota Cui   +12 more
wiley   +1 more source

Pathogenicity and virulence of Clostridium botulinum

Virulence, 2023
Clostridium botulinum, a polyphyletic Gram-positive taxon of bacteria, is classified purely by their ability to produce botulinum neurotoxin (BoNT). BoNT is the primary virulence factor and the causative agent of botulism.
Alexander M. Rawson, Andrew W. Dempster, Christopher M. Humphreys, Nigel P. Minton   +3 more
doaj   +1 more source

Food Safety and Nutritional Aspects of Plant‐Based Dairy and Meat Alternatives: A Review

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Plant‐based dairy and meat alternatives (PBDA and PBMA) offer sustainability benefits but also introduce chemical and microbiological hazards to the diet. Key concerns include emerging mycotoxins, heavy metals, process contaminants, and heat‐resistant spore‐forming bacteria.
Elina Sohlberg, Petra Pasonen, Hanna‐Leena Alakomi, Johanna Suomi   +3 more
wiley   +1 more source

Case report: Aberrant fecal microbiota composition of an infant diagnosed with prolonged intestinal botulism

Gut Pathogens
Background Intestinal botulism is primarily reported in small babies as a condition known as infant botulism. The condition results from the ingestion of environmental or foodborne spores of botulinum neurotoxin (BoNT) producing Clostridia, usually ...
François P. Douillard, Yağmur Derman, Ching Jian, Katri Korpela, Harri Saxén, Anne Salonen, Willem M. de Vos, Hannu Korkeala, Miia Lindström   +8 more
doaj   +1 more source

Botulism in the 21st Century: A Scoping Review

Brown Journal of Hospital Medicine, 2023
Botulism is a potentially deadly neuroparalytic disease that affects all age groups; it is highly challenging to diagnose due to its nonspecific symptoms. Infant botulism is the most common form of botulism in the United States, followed by foodborne and
Ketino Kobaidze, Zanthia Wiley
doaj  

The dilemma of diagnosing wound botulism in an infant: A rare case of paralysis with topical application of honey

International Journal of Infectious Diseases, 2020
Botulism is a form of paralysis caused by a neurotoxin produced by the bacterium Clostridium botulinum. It is well known that natural honey contains Clostridium botulinum spores; controversy arises when a honey-related product is being used for wound ...
Mohd Islahuddin Mohd Tamrin
doaj   +1 more source

Laboratory investigation of the first infant botulism case caused by type E botulinum neurotoxin producing Clostridium butyricum in China

Zhongguo shipin weisheng zazhi, 2020
Objective Laboratory investigation was performed on a suspected case of infant botulism. Methods Thirty samples of stool, left-over food and environment swabs related to the case were collected, Clostridium spp.
Yinping DONG, Tao JIANG, Shuai ZHAO, Yu MU, Jin XU, Wei WANG, Ran SHI, Fengqin LI   +7 more
doaj   +1 more source

Adult Intestinal Botulism: A Rare Presentation in an Immunocompromised Patient With Short Bowel Syndrome

Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2018
The cholinergic heat-labile neurotoxin produced by Clostridium species is primarily responsible for the clinical manifestations of botulism. The classic phenotypic presentation of botulism consists of subacute descending flaccid paralysis with intact ...
Pramod K. Guru, MBBS, MD, Tara L. Becker, MD, Alana Stephens, DO, Rocco J. Cannistraro, MD, Benjamin H. Eidelman, MD, D. Jane Hata, PhD, Lisa Brumble, MD   +6 more
doaj   +1 more source