Results 81 to 90 of about 3,629,832 (290)

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

open access: yesAdvanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang   +12 more
wiley   +1 more source

Health-promoting properties of bioactive peptides derived from milk proteins in infant food: a review

open access: yesDairy Science and Technology, 2013
Milk proteins have attracted extensive interest in terms of their bioavailability following ingestion. Enzymatic digestion of dairy products generates numerous peptides with various biological activities.
Vassilios Raikos, Theodore Dassios
semanticscholar   +1 more source

A Natural Sweetener‐inducible Genetic Switch Controls Therapeutic Protein Expression in Mammals

open access: yesAdvanced Science, EarlyView.
This study develops a natural sweetener, the psicose‐inducible transgene expression (PURE) system based on an Agrobacterium tumefaciens–derived transcriptional repressor PsiR. The PURE system is highly specific to psicose, being insensitive to other sugars and structurally similar molecules.
Longliang Qiao   +16 more
wiley   +1 more source

Timing of Allergenic Food Introduction to the Infant Diet and Risk of Allergic or Autoimmune Disease: A Systematic Review and Meta-analysis.

open access: yesJournal of the American Medical Association (JAMA), 2016
Importance Timing of introduction of allergenic foods to the infant diet may influence the risk of allergic or autoimmune disease, but the evidence for this has not been comprehensively synthesized.
D. Ierodiakonou   +14 more
semanticscholar   +1 more source

Paving the Way to Elucidate Hg's Role in Tumorigenesis

open access: yesAdvanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li   +10 more
wiley   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

Microbiological evaluation of infant foods quality and molecular detection of Bacillus cereus toxins relating genes

open access: yesToxicology Reports, 2018
A 205 samples representing eight different infant foods with various based materials were collected and analyzed for their microbiological properties. The contamination rate by aerobic spore formers was achieved 100% in milk based infant food with fruit,
Zeinab I. Sadek   +4 more
doaj   +1 more source

SR‐B1‐Mediated Transplacental Transfer of Hydrophobic Toxicants Disrupts Fetal Development During Barriergenesis

open access: yesAdvanced Science, EarlyView.
This study maps the spatiotemporal distribution of hydrophobic toxicants and endogenous metabolites in the developing placenta and fetus. By integrating mass spectrometry imaging with snRNA‐seq, we identify SR‐B1 as a key transporter driving early‐gestation xenobiotic transfer and reveal a critical exposure window associated with persistent fetal ...
Yixuan Huang   +10 more
wiley   +1 more source

Extracellular Vesicles in Autoimmune Diseases: From Diagnostic Biomarkers to Engineered Therapeutics

open access: yesAdvanced Science, EarlyView.
This review provides a systematic comparison of extracellular vesicles (EVs) from both mammalian and plant sources in the context of autoimmune diseases. It highlights their emerging roles as precision biomarkers and engineered therapeutic platforms.
Yufei Wu   +6 more
wiley   +1 more source

BRAIN STORMING AND DEMONSTRATION CHANGE MOTHER’S BEHAVIOR TOWARD BREASTMILK COMPANION FOOD

open access: yesJurnal Ners, 2017
Introduction: Infant on 0-6 months must be gotten exclusive breast milk from their mother for growth and development status. It was mean that no other food for infant.
Mira Triharini   +2 more
doaj   +1 more source

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