Results 191 to 200 of about 9,861 (247)
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Electroclinical Landscape of Infantile Epileptic Spasms Syndrome
Indian Journal of PediatricsTo elucidate the electroclinical characteristics of infantile epileptic spasms syndrome (IESS) and to determine any potential association among these with underlying etiologies and response to therapy.Sixty-eight, treatment-naive children with IESS underwent long-term video electroencephalogram (EEG) recording, which was used to characterize the ...
Pankaj Pal +8 more
semanticscholar +3 more sources
Infantile Epileptic Encephalopathy with Hypsarrhythmia (Infantile Spasms/West Syndrome)
Journal of Clinical Neurophysiology, 2003Infantile spasms is a unique disorder peculiar to infancy and early childhood. In this article, the clinical manifestations and electroencephalographic features of the disorder are described. The possible pathophysiologic mechanisms underlying infantile spasms and the relation of this disorder to other childhood encephalopathies are discussed. Finally,
Richard A, Hrachovy, James D, Frost
openaire +2 more sources
Delays to care in infantile epileptic spasms syndrome: Racial and ethnic inequities
Epilepsia, 2023AbstractObjectiveNon‐Hispanic (NH) Black children are less likely to receive a standard treatment course for infantile epileptic spasms syndrome (IESS) than White/NH children at pediatric tertiary care epilepsy centers in the United States. However, if inequities exist in time to diagnosis is unknown.
Christina Briscoe Abath +14 more
openaire +2 more sources
Epilepsia
OBJECTIVE This single-center retrospective study examined the response to initial standard therapy in children with infantile epileptic spasms syndrome (IESS) associated with surgically-remediable lesion and evaluated the risk factors for drug resistance.
Avantika Singh +12 more
semanticscholar +1 more source
OBJECTIVE This single-center retrospective study examined the response to initial standard therapy in children with infantile epileptic spasms syndrome (IESS) associated with surgically-remediable lesion and evaluated the risk factors for drug resistance.
Avantika Singh +12 more
semanticscholar +1 more source
Clinical Neurophysiology, 2022
This study aimed to determine the correlation between outcomes following adrenocorticotrophic hormone (ACTH) therapy and measurements of relative power spectrum (rPS), weighted phase lag index (wPLI), and graph theoretical analysis on pretreatment electroencephalography (EEG) in infants with non-lesional infantile epileptic spasms syndrome (IESS ...
Sotaro, Kanai +11 more
openaire +2 more sources
This study aimed to determine the correlation between outcomes following adrenocorticotrophic hormone (ACTH) therapy and measurements of relative power spectrum (rPS), weighted phase lag index (wPLI), and graph theoretical analysis on pretreatment electroencephalography (EEG) in infants with non-lesional infantile epileptic spasms syndrome (IESS ...
Sotaro, Kanai +11 more
openaire +2 more sources
Indian Journal of Pediatrics
The study evaluated the short-term effectiveness and tolerability of vigabatrin therapy in children with infantile epileptic spasms syndrome (IESS). Children with IESS were enrolled within two weeks of initiation of vigabatrin and prospectively followed up to 12 wk for complete cessation of epileptic spasms (ES) and occurrence of adverse events. Of 107
Shikha Sharma +8 more
semanticscholar +3 more sources
The study evaluated the short-term effectiveness and tolerability of vigabatrin therapy in children with infantile epileptic spasms syndrome (IESS). Children with IESS were enrolled within two weeks of initiation of vigabatrin and prospectively followed up to 12 wk for complete cessation of epileptic spasms (ES) and occurrence of adverse events. Of 107
Shikha Sharma +8 more
semanticscholar +3 more sources
Infantile epileptic spasms syndrome: When spasms come out of the blue
Epilepsy & BehaviorThis study evaluates the electroclinical features of infantile epileptic spasms syndrome (IESS) suddenly appearing in previously normal patients, aiming to describe clinical outcomes and independent predictors.We retrospectively selected a homogeneous group of patients with IESS from two Italian centers.
Marta, Conti +9 more
openaire +2 more sources
Response to nitrazepam in infantile epileptic spasms syndrome after failed standard treatment
Epilepsy & BehaviorOver half of children with infantile epileptic spasms syndrome (IESS) do not respond to standard treatments. Nitrazepam has shown efficacy similar to adrenocorticotrophic hormone. This study evaluated response rates, adverse effects of nitrazepam, and factors associated with responders in children with IESS who failed standard treatment.We conducted a ...
Sunichaya Areekul +5 more
semanticscholar +3 more sources
Journal of Child Neurology
Background: Infantile epileptic spasms syndrome is an epileptic encephalopathy with poor prognosis. Objective: To describe clinical features and predictors of unfavorable outcomes of infantile epileptic spasms syndrome in a multiancestry cohort. Methods:
Dana Thaher +2 more
semanticscholar +1 more source
Background: Infantile epileptic spasms syndrome is an epileptic encephalopathy with poor prognosis. Objective: To describe clinical features and predictors of unfavorable outcomes of infantile epileptic spasms syndrome in a multiancestry cohort. Methods:
Dana Thaher +2 more
semanticscholar +1 more source
Journal of Pineal Research, 2023
This was a prospective, randomized, double‐blind, single‐center placebo‐controlled trial to assess the efficacy and safety of melatonin as an add‐on treatment for infantile epileptic spasms syndrome (IESS).
Yulin Sun +12 more
semanticscholar +1 more source
This was a prospective, randomized, double‐blind, single‐center placebo‐controlled trial to assess the efficacy and safety of melatonin as an add‐on treatment for infantile epileptic spasms syndrome (IESS).
Yulin Sun +12 more
semanticscholar +1 more source