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Brain Magnetic Resonance Imaging Findings in Infantile Spasms [PDF]
Background: Infantile spasms are an age-specific epileptic disorder. They occur in infancy and early childhood. They can be caused by multiple etiologies. Structural abnormalities represent an important cause of infantile spasms. Brain magnetic resonance
Osama Y. Muthaffar
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Clinical profile and treatment of infantile spasms using vigabatrin and ACTH - a developing country perspective [PDF]
Background Infantile spasms represent a serious epileptic syndrome that occurs in the early infantile age. ACTH and Vigabatrin are actively investigated drugs in its treatment.
Ishaque Sidra+3 more
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Although the syndrome of infantile spasms has been known for 150 years and its treatment described since 1958, controversy still surrounds the appropriate therapy for this devastating disorder. The rationale, dosage, and side effects of ACTH treatment of infantile spasms is described.
J Gordon Millichap
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The Epidemiology of Infantile Spasms [PDF]
Objective:The aim of this study was to estimate population based incidence rates for infantile spasms (IS) and to study our clinical impression that the incidence of IS has recently decreased in the Canadian Provinces of Nova Scotia and Prince Edward Island.Methods:Birth cohorts from 1978 to 1998, identified through the hospital health records, EEG ...
Paula Brna+3 more
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Epileptic spasms relapse is associated with response latency but not conventional attributes of post‐treatment EEG [PDF]
Objective Relapse of epileptic spasms after initial treatment of infantile epileptic spasms syndrome (IESS) is common. However, past studies of small cohorts have inconsistently linked relapse risk to etiology, treatment modality, and EEG features upon ...
Emmi Deckard+7 more
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Limited efficacy of zonisamide in the treatment of refractory infantile spasms [PDF]
A series of relatively small studies collectively suggest that zonisamide may be effective in the treatment of infantile spasms. Using a large single‐center cohort of children with infantile spasms, we set out to evaluate the efficacy and safety of ...
Shaun A. Hussain+7 more
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Current trends in the treatment of infantile spasms [PDF]
Chang-Yong TsaoClinical Pediatrics and Neurology, The Ohio State University, College of Medicine, Columbus, Ohio, USAAbstract: Infantile spasms are an epilepsy syndrome with distinctive features, including age onset during infancy, characteristic ...
Chang-Yong Tsao
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Four infants with partial seizures evolving to infantile spasms were investigated using simultaneous EEG-video-telemetry recording in the Dept of Pediatrics, Nagoya University, Nagoya, and Division of Pediatric Neurology, Central Hospital, Aichi ...
J Gordon Millichap
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Clinical profile of vigabatrin as monotherapy for treatment of infantile spasms [PDF]
Jason T Lerner1, Noriko Salamon2, Raman Sankar1,31Departments of Pediatrics, 2Radiological Sciences, 3Neurology, David Geffen School of Medicine, University of California Los Angeles and Mattel Children’s Hospital at UCLA, Los Angeles, CA ...
Jason T Lerner+2 more
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UK Infantile Spasms Study: Effect of Time to Treatment and Age at Onset on Developmental Outcome [PDF]
The effects of lead time to treatment (time from onset of spasms to start of treatment), age at onset of spasms, etiology, and treatment on developmental outcome at 4 years were investigated using multiple linear regression in 77 infants with spasms ...
J Gordon Millichap
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