Results 1 to 10 of about 9,475 (246)

Brain Magnetic Resonance Imaging Findings in Infantile Spasms [PDF]

open access: yesNeurology International, 2022
Background: Infantile spasms are an age-specific epileptic disorder. They occur in infancy and early childhood. They can be caused by multiple etiologies. Structural abnormalities represent an important cause of infantile spasms. Brain magnetic resonance
Osama Y. Muthaffar
doaj   +2 more sources

Treatment of Infantile Spasms

open access: hybridPediatric Neurology, 1990
Although the syndrome of infantile spasms has been known for 150 years and its treatment described since 1958, controversy still surrounds the appropriate therapy for this devastating disorder. The rationale, dosage, and side effects of ACTH treatment of infantile spasms is described.
J Gordon Millichap
  +9 more sources

The Epidemiology of Infantile Spasms [PDF]

open access: bronzeCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2001
Objective:The aim of this study was to estimate population based incidence rates for infantile spasms (IS) and to study our clinical impression that the incidence of IS has recently decreased in the Canadian Provinces of Nova Scotia and Prince Edward Island.Methods:Birth cohorts from 1978 to 1998, identified through the hospital health records, EEG ...
Paula Brna   +3 more
openalex   +4 more sources

Infantile Spasms

open access: yesPediatric Neurology Briefs, 1988
Four infants with partial seizures evolving to infantile spasms were investigated using simultaneous EEG-video-telemetry recording in the Dept of Pediatrics, Nagoya University, Nagoya, and Division of Pediatric Neurology, Central Hospital, Aichi ...
J Gordon Millichap
doaj   +3 more sources

UK Infantile Spasms Study: Effect of Time to Treatment and Age at Onset on Developmental Outcome [PDF]

open access: hybridPediatric Neurology Briefs, 2011
The effects of lead time to treatment (time from onset of spasms to start of treatment), age at onset of spasms, etiology, and treatment on developmental outcome at 4 years were investigated using multiple linear regression in 77 infants with spasms ...
J Gordon Millichap
doaj   +2 more sources

Infantile Spasms in Pediatric Down Syndrome: Potential Mechanisms Driving Therapeutic Considerations [PDF]

open access: yesChildren
Infantile spasms are common in Down Syndrome (DS), but the mechanisms by which DS predisposes to this devastating epilepsy syndrome are unclear.
Carl E. Stafstrom, Li-Rong Shao
doaj   +2 more sources

A pulse rapamycin therapy for infantile spasms and associated cognitive decline

open access: yesNeurobiology of Disease, 2011
Infantile spasms are seizures manifesting within a spectrum of epileptic encephalopathies of infancy that often lead to cognitive impairment. Their current therapies, including adrenocorticotropic hormone (ACTH), high dose steroids, or vigabatrin, are ...
Aristea S Galanopoulou
exaly   +3 more sources

Confirmation of infantile spasms resolution by prolonged outpatient EEGs [PDF]

open access: yesEpilepsia Open, 2021
Objective There is no consensus on the type or duration of the posttreatment EEG needed for assessing treatment response for infantile spasms (IS). We assessed whether outpatient electroencephalograms (EEGs) are sufficient to confirm infantile spasms (IS)
Christopher J. Yuskaitis   +4 more
doaj   +2 more sources

Infantile spasms and pigmentary mosaicism [PDF]

open access: bronzeEpilepsia, 2009
SummaryWe present a 3‐year‐old boy with pigmentary mosaicism and persistent intractable infantile spasms due to mosaicism of chromosome 7. Getting the diagnosis of pigmentary mosaicism in a child with infantile spasms may not be easy, as most diagnostic work‐up is done in infancy, at a time when skin manifestations can be subtle. We stress the need for
Lars Hansen, Anette Bygum, Lotte Krogh
openalex   +5 more sources

Prognosis of Infantile Spasms

open access: yesPediatric Neurology Briefs, 1993
The developmental, neurologic, and seizure outcome and prognostic factors of 57 cases of infantile spasms were evaluated in relation to etiology (cryptogenic 17 cases, symptomatic 40 cases) at the Hospital for Sick Children, Toronto, Canada.
J Gordon Millichap
doaj   +3 more sources

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