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Seizure Prediction Analysis of Infantile Spasms [PDF]

IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2023
Infantile spasms (IS) is a typical childhood epileptic disorder with generalized seizures. The sudden, frequent and complex characteristics of infantile spasms are the main causes of sudden death, severe comorbidities and other adverse consequences ...
Runze Zheng, Jiuwen Cao, Yuanmeng Feng, Xiaodan Zhao, Tiejia Jiang, Feng Gao   +5 more
doaj   +2 more sources

Brain Magnetic Resonance Imaging Findings in Infantile Spasms [PDF]

Neurology International, 2022
Background: Infantile spasms are an age-specific epileptic disorder. They occur in infancy and early childhood. They can be caused by multiple etiologies. Structural abnormalities represent an important cause of infantile spasms. Brain magnetic resonance
Osama Y. Muthaffar
doaj   +2 more sources

A team science approach to discover novel targets for infantile spasms (IS) [PDF]

Epilepsia Open, 2021
Infantile spasms (IS) is a devastating epilepsy syndrome that typically begins in the first year of life. Symptoms consist of stereotypical spasms, developmental delay, and electroencephalogram (EEG) that may demonstrate Hypsarhythmia.
The CURE Infantile Spasms Consortium, CURE Staff, Laura Lubbers, Sloka S. Iyengar   +2 more
doaj   +2 more sources

Infantile Spasms in Pediatric Down Syndrome: Potential Mechanisms Driving Therapeutic Considerations [PDF]

Children
Infantile spasms are common in Down Syndrome (DS), but the mechanisms by which DS predisposes to this devastating epilepsy syndrome are unclear.
Carl E. Stafstrom, Li-Rong Shao
doaj   +2 more sources

Confirmation of infantile spasms resolution by prolonged outpatient EEGs [PDF]

Epilepsia Open, 2021
Objective There is no consensus on the type or duration of the posttreatment EEG needed for assessing treatment response for infantile spasms (IS). We assessed whether outpatient electroencephalograms (EEGs) are sufficient to confirm infantile spasms (IS)
Christopher J. Yuskaitis, Kate Mysak, Brianna Godlewski, Bo Zhang, Chellamani Harini   +4 more
doaj   +2 more sources

Inequities in Therapy for Infantile Spasms: A Call to Action. [PDF]

Ann Neurol, 2022
Baumer FM, Mytinger JR, Neville K, Briscoe Abath C, Gutierrez CA, Numis AL, Harini C, He Z, Hussain SA, Berg AT, Chu CJ, Gaillard WD, Loddenkemper T, Pasupuleti A, Samanta D, Singh RK, Singhal NS, Wusthoff CJ, Wirrell EC, Yozawitz E, Knupp KG, Shellhaas RA, Grinspan ZM, Pediatric Epilepsy Research Consortium, National Infantile Spasms Consortium.   +24 more
europepmc   +3 more sources

Novel neurosteroid pregnanolone pyroglutamate suppresses neurotoxicity syndrome induced by tetramethylenedisulfotetramine but is ineffective in a rodent model of infantile spasms. [PDF]

Pharmacol Rep, 2023
Chern CR, Lauková M, Schonwald A, Kudová E, Chodounská H, Chern CJ, Shakarjian MP, Velíšková J, Velíšek L.   +8 more
europepmc   +3 more sources

Pathophysiology of Infantile Spasms [PDF]

Pediatric Neurology Briefs, 1993
An age-specific endogenous-convulsant hypothesis implicating corticotropin-releasing hormone (CRH), an excitant neuropeptide suppressed by ACTH/steroids, is proposed for the pathophysiology of massive infantile spasms in a report from the University of ...
J Gordon Millichap
doaj   +2 more sources

The gut microbiome and the ketogenic diet: A pathway towards treatment optimization in infantile spasms. [PDF]

EBioMedicine, 2022
McCafferty C.
europepmc   +2 more sources

Seizure modulation by the gut microbiota and tryptophan-kynurenine metabolism in an animal model of infantile spasms [PDF]

EBioMedicine, 2022
Chunlong Mu, Shyamchand Mayengbam, Jong M Rho   +2 more
exaly   +2 more sources