Results 101 to 110 of about 9,475 (246)

Clioquinol as a new therapy in epilepsy: From preclinical evidence to a proof‐of‐concept clinical study

Epilepsia, EarlyView.
Abstract Objective Drug‐resistant epilepsy (DRE) affects >25 million people worldwide and is often associated with neuroinflammation. Increasing evidence links deficiency or malfunctioning of the enzyme phosphoglycerate dehydrogenase (PHGDH), which converts 3‐phosphoglycerate to generate serine and the neurotransmitter glycine, with (drug‐resistant ...
Karin Thevissen, Annelii Ny, Daniëlle Copmans, Jana Tits, Kenichi Kamata, Eva Gielis, Kevin Longin, Jo Sourbron, Peravina Thergarajan, Tracie Huey‐Lin Tan, Idrish Ali, Nigel C. Jones, Terence J. O'Brien, Mastura Monif, Bridgette D. Semple, Christine Germeys, Benedetta Frizzi, Virginia Minniti, Sebastian Perrone, Carole L. Linster, Ilaria Elia, Ludo Van Den Bosch, Bruno P. A. Cammue, Arnout Voet, Lieven Lagae, Peter de Witte   +25 more
wiley   +1 more source

EEG biomarkers for the diagnosis and treatment of infantile spasms. [PDF]

Front Neurol, 2022
Romero Milà B, Remakanthakurup Sindhu K, Mytinger JR, Shrey DW, Lopour BA.   +4 more
europepmc   +1 more source

Epileptogenesis in meningioma: Theories, putative biomarkers, and postoperative risk

Epilepsia, EarlyView.
Abstract Cranial meningioma are the most common type of primary brain tumor, and focal onset, tumor‐related seizures affect a significant proportion of patients. Seizures affect 30% of symptomatic preoperative patients and a further 12% of postoperative patients.
William H. Cook, Conor S. Gillespie, Ali Bakhsh, Anthony G. Marson, Michael D. Jenkinson, Adel E. Helmy   +5 more
wiley   +1 more source

Response to magnesium sulfate and adrenocorticotropic hormone combination therapy for infantile spasms with failed first-line treatments. [PDF]

Pediatr Investig, 2023
Wang Q, He W, Wang Y, Liu L, Zhang M, Yang X, Zou L.   +6 more
europepmc   +1 more source

Presence of interictal epileptiform EEG discharges implies increased risk of recurrence after the first unprovoked seizure: Report of the International League Against Epilepsy and International Federation of Clinical Neurophysiology

Epilepsia, EarlyView.
Abstract Objective A joint International Federation of Clinical Neurophysiology–International League Against Epilepsy (IFCN‐ILAE) Taskforce was created to explore the published evidence for initial EEG recordings in the evaluation of patients who experienced their first unprovoked seizure, and to determine the diagnostic value of EEG in supporting the ...
Betül Baykan, John Dunne, Samuel Wiebe, Louis Maillard, Sandor Beniczky, Michalis Koutroumanidis, Margitta Seeck   +6 more
wiley   +1 more source

Clinical profile of vigabatrin as monotherapy for treatment of infantile spasms

Neuropsychiatric Disease and Treatment, 2010
Jason T Lerner1, Noriko Salamon2, Raman Sankar1,31Departments of Pediatrics, 2Radiological Sciences, 3Neurology, David Geffen School of Medicine, University of California Los Angeles and Mattel Children’s Hospital at UCLA, Los Angeles, CA ...
Jason T Lerner, Noriko Salamon, Raman Sankar   +2 more
doaj  

Adapting Action Recognition Neural Networks for Automated Infantile Spasm Detection

IEEE Transactions on Neural Systems and Rehabilitation Engineering
Infantile spasms are a severe epileptic syndrome characterized by short muscular contractions lasting from 0.5 to 2 seconds. They are often misdiagnosed due to their atypical presentation, and treatment is frequently delayed, leading to stagnation or ...
Samuel Diop, Nouha Essid, Francois Jouen, Jean Bergounioux, Imen Trabelsi   +4 more
doaj   +1 more source

Vigabatrin-associated brain abnormalities on MRI in tuberous sclerosis complex patients with infantile spasms: are they preventable? [PDF]

Ther Adv Neurol Disord, 2022
Wan L, He W, Wang YY, Xu Y, Lu Q, Zhang MN, Wang QH, Dun S, Liu LY, Shi XY, Wang J, Hu LY, Zhang B, Yang G, Zou LP.   +14 more
europepmc   +1 more source

Enlargement of cardiac rhabdomyoma and myocardial ischaemia during corticotropin treatment for infantile spasm [PDF]

, 2000
Sayuri Hiraishi
openalex   +1 more source

Absence seizures and sleep–wake abnormalities in a rat model of GRIN2B neurodevelopmental disorder

Epilepsia, EarlyView.
Abstract Objective Pathogenic mutations in GRIN2B are an important cause of severe neurodevelopmental disorders resulting in epilepsy, autism, and intellectual disability. GRIN2B encodes the GluN2B subunit of N‐methyl‐d‐aspartate receptors (NMDARs), which are ionotropic glutamate receptors critical for normal development of the nervous system and ...
Katerina Hristova, Melissa C. M. Fasol, Niamh McLaughlin, Mohammad Sarfaraz Nawaz, Mehmet Taskiran, Ingrid Buller‐Peralta, Anjanette P. Harris, Andrew Sutherland, Alejandro Bassi, Adrian Ocampo‐Garces, Javier Escudero, Peter C. Kind, Alfredo Gonzalez‐Sulser   +12 more
wiley   +1 more source