Results 11 to 20 of about 9,475 (246)

Asymmetric Infantile Spasms

Pediatric Neurology Briefs, 1995
Behavioral and EEG asymmetry and asynchrony of 8,680 infantile spasms were analysed in a review of 75 consecutive video-EEG recordings performed at UCLA Medical Center, Los Angeles from 1982 to 1992.
J Gordon Millichap
doaj   +4 more sources

Pathophysiology of Infantile Spasms

Pediatric Neurology Briefs, 1993
An age-specific endogenous-convulsant hypothesis implicating corticotropin-releasing hormone (CRH), an excitant neuropeptide suppressed by ACTH/steroids, is proposed for the pathophysiology of massive infantile spasms in a report from the University of ...
J Gordon Millichap
doaj   +3 more sources

Methysergide and Infantile Spasms

Pediatric Neurology Briefs, 1989
A trial of antiadrenergic and antiseretonergic drugs in the treatment of 24 newly diagnosed and previously untreated infantile spasm patients is reported from the Epilepsy Research Center, Section of Neurophysiology, Department of Neurology, Baylor ...
J Gordon Millichap
doaj   +4 more sources

ACTH in Infantile Spasms

Pediatric Neurology Briefs, 1990
The relationship between dose of ACTH and the initial effect and long-term prognosis was investigated in 41 children with infantile spasms at the Department of Pediatrics, Kyoto University, Kyoto, Japan.
J Gordon Millichap
doaj   +3 more sources

The effect of lead time to treatment and of age of onset on developmental outcome at 4 years in infantile spasms: Evidence from the United Kingdom Infantile Spasms Study

Epilepsia, 2011
Finbar O’Callaghan, Andrew Lux, Katrina Darke, Stuart W. Edwards, Eleanor Hancock, Anthony L. Johnson, Colin Kennedy, Richard Newton, Christopher Verity, John Osborne   +9 more
exaly   +2 more sources

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source

Seizure Prediction Analysis of Infantile Spasms

IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2023
Infantile spasms (IS) is a typical childhood epileptic disorder with generalized seizures. The sudden, frequent and complex characteristics of infantile spasms are the main causes of sudden death, severe comorbidities and other adverse consequences ...
Runze Zheng, Jiuwen Cao, Yuanmeng Feng, Xiaodan Zhao, Tiejia Jiang, Feng Gao   +5 more
doaj   +1 more source

Brazilian experts' consensus on the treatment of infantile epileptic spasm syndrome in infants

Arquivos de Neuro-Psiquiatria, 2023
Background Infantile epileptic spasms syndrome (IESS) is a rare but severe condition affecting children early and is usually secondary to an identifiable brain disorder.
Letícia Pereira de Brito Sampaio, Adélia Maria de Miranda Henriques-Souza, Mariana Ribeiro Marcondes da Silveira, Lisiane Seguti, Mara Lúcia Schmitz Ferreira Santos, Maria Augusta Montenegro, Sérgio Antoniuk, Maria Luíza Giraldes de Manreza   +7 more
doaj   +1 more source

Teleneurology based management of infantile spasms during COVID-19 pandemic: A consensus report by the South Asia Allied West syndrome research group

Epilepsy & Behavior Reports, 2021
With telehealth services rescuing patients with chronic neurological disorders during the COVID-19 pandemic, there is a need for simplified teleneurology protocols for neurological disorders in children.
Priyanka Madaan, Jitendra Kumar Sahu, Jithangi Wanigasinghe, Kanij Fatema, Kyaw Linn, Mimi Lhamu Mynak, Nicolás Garófalo Gómez, Pauline Samia, Prakash Poudel, Prem Chand, Raili Riikonen   +10 more
doaj   +1 more source

Infantile Spasms

Pediatric Clinics of North America, 1989
Infantile spasms are a unique disorder of infancy and early childhood. The average age at onset of infantile spasms is 6 months and the average incidence of the disorder is approximately 0.31 per 1000 live births. Approximately one-quarter of patients will spontaneously stop having spasms within 1 year of onset.
Richard A. Hrachovy, James D. Frost
openaire   +5 more sources