Results 31 to 40 of about 141,590 (258)
Methysergide and Infantile Spasms
Pediatric Neurology Briefs, 1989 A trial of antiadrenergic and antiseretonergic drugs in the treatment of 24 newly diagnosed and previously untreated infantile spasm patients is reported from the Epilepsy Research Center, Section of Neurophysiology, Department of Neurology, Baylor ...
J Gordon Millichap
doaj +4 more sources
Pathophysiology of Infantile Spasms
Pediatric Neurology Briefs, 1993 An age-specific endogenous-convulsant hypothesis implicating corticotropin-releasing hormone (CRH), an excitant neuropeptide suppressed by ACTH/steroids, is proposed for the pathophysiology of massive infantile spasms in a report from the University of ...
J Gordon Millichap
doaj +3 more sources
Orphanet Journal of Rare Diseases, 2018 Background Infantile spasms represent the catastrophic, age-specific seizure type associated with acute and long-term neurological morbidity. However, due to rarity and heterogenous determination, there is persistent uncertainty of its pathophysiological
Jason L. Jia +4 more
doaj +2 more sources
Pediatric Neurology Briefs, 1990 The relationship between dose of ACTH and the initial effect and long-term prognosis was investigated in 41 children with infantile spasms at the Department of Pediatrics, Kyoto University, Kyoto, Japan.
J Gordon Millichap
doaj +3 more sources
Comparative Effectiveness of Initial Treatment for Infantile Spasms in a Contemporary US Cohort. [PDF]
Neurology, 2021 Objective To compare the effectiveness of initial treatment for infantile spasms. Methods The National Infantile Spasms Consortium prospectively followed up children with new-onset infantile spasms that began at age 2 to 24 months at 23 US centers (2012 ...
Grinspan ZM +21 more
europepmc +2 more sources
Epilepsia Open, 2023 Literature on the genotypic spectrum of Infantile Epileptic Spasms Syndrome (IESS) in children is scarce in developing countries. This multicentre collaboration evaluated the genotypic and phenotypic landscape of genetic IESS in Indian children.
Balamurugan Nagarajan +23 more
semanticscholar +1 more source
Mechanisms of infantile epileptic spasms syndrome: What have we learned from animal models?
Epilepsia, 2023 The devastating developmental and epileptic encephalopathy of infantile epileptic spasms syndrome (IESS) has numerous causes, including, but not limited to, brain injury, metabolic, and genetic conditions.
Andy Cheuk-Him Ng +4 more
semanticscholar +1 more source
Tuber Locations Associated with Infantile Spasms Map to a Common Brain Network
Annals of Neurology, 2021 Approximately 50% of patients with tuberous sclerosis complex develop infantile spasms, a sudden onset epilepsy syndrome associated with poor neurological outcomes.
A. Cohen +16 more
semanticscholar +1 more source
Epilepsia, 2023 This study was undertaken to evaluate our treatment algorithm for infantile epileptic spasms syndrome (IESS) used between 2000 and 2018.
M. Kuchenbuch +4 more
semanticscholar +1 more source
Brain Communications, 2021 Infantile spasms (IS) syndrome is a catastrophic, epileptic encephalopathy of infancy that is often refractory to current antiepileptic therapies. The ketogenic diet (KD) has emerged as an alternative treatment for patients with medically intractable ...
Anamika Choudhary +8 more
semanticscholar +1 more source