Results 81 to 90 of about 141,590 (258)

Infantile Spasms: Opportunities to Improve Care

Seminars in neurology, 2020
Infantile spasm (IS) is a distinct epilepsy syndrome characterized by epileptic spasms (the clinical seizure type) and hypsarrhythmia (the electrographic abnormality). IS is frequently accompanied by impaired neurodevelopment and is often associated with
Ricka Messer, K. Knupp
semanticscholar   +1 more source

The underlying etiology of infantile spasms (West syndrome): Information from the International Collaborative Infantile Spasms Study (ICISS)

Epilepsia, 2019
To determine the underlying etiologies in a contemporary cohort of infants with infantile spasms and to examine response to treatment.
John Osborne, Stuart W. Edwards, Fabienne Dietrich Alber, Eleanor Hancock, Anthony L. Johnson, Colin Kennedy, Marcus Likeman, Andrew Lux, Mark T. Mackay, Andrew A. Mallick, Richard Newton, Melinda Nolan, Ronit Pressler, D. Rating, Bernhard Schmitt, Christopher Verity, Finbar O’Callaghan   +16 more
openalex   +2 more sources

Infantile spams without hypsarrhythmia: A study of 16 cases [PDF]

, 2010
In this study, we present the electroclinical features and evolution of patients with epileptic spasms (ES) in clusters without hypsarrhythmia and with or without focal or generalized paroxysmal discharges on the interictal EEG.
Caraballo, Roberto Horacio, Ruggieri, Victor, Gonzalez, Gabriel, Cersósimo, Ricardo, Gamboni, Beatriz, Rey, Andrea, Poveda, Juan Carlos Perez, Dalla Bernardina, Bernardo   +7 more
core   +1 more source

Longer Duration of Epilepsy and Earlier Age at Epilepsy Onset Correlate with Impaired Cognitive Development in Infancy [PDF]

, 2009
We assessed the impact of age at onset of epilepsy and duration and frequency of seizures on cognitive development in children less than 3 years old. Retrospective analysis was conducted on clinical data and neuropsychological testing of 33 infants with ...
Vendrame, Martina
core   +2 more sources

A pulse rapamycin therapy for infantile spasms and associated cognitive decline

Neurobiology of Disease, 2011
Infantile spasms are seizures manifesting within a spectrum of epileptic encephalopathies of infancy that often lead to cognitive impairment. Their current therapies, including adrenocorticotropic hormone (ACTH), high dose steroids, or vigabatrin, are ...
Emmanuel Raffo, Antonietta Coppola, Tomonori Ono, Stephen W. Briggs, Aristea S. Galanopoulou   +4 more
doaj  

Treatment of Symptomatic Infantile Spasms

Pediatric Neurology Briefs, 2013
Investigators at Tokyo Women's Medical University studied the clinical, radiological, and EEG characteristics of 69 patients with infantile spasms (IS) followed for 3-74 months (mean 18 months) after initial cessation of epileptic spasms (ES).
J Gordon Millichap
doaj   +1 more source

Study of the Effects of Mogadon in Treatment of Infantile Spasms

پزشکی بالینی ابن سینا, 2001
Among epileptic syndromes the infantile spasms ( west syndrome ) is the    most  malignant one and leads to  irreparable brain damage, which is    related directly to duration of spasms.
Mohammad Mahdi Taghdiri
doaj  

A Systematic Literature Review and Indirect Treatment Comparison of Efficacy of Repository Corticotropin Injection versus Synthetic Adrenocorticotropic Hormone for Infantile Spasms

Journal of Health Economics and Outcomes Research, 2021
**Background:** Infantile spasms is a rare disease characterized by distinct seizures and hypsarrhythmia. Adrenocorticotropic hormone (ACTH) is available as a natural product (repository corticotropin injection, [RCI]; Acthar® Gel) and as synthetic ...
Michael S. Duchowny, Ishveen Chopra, John Niewoehner, George J. Wan, Beth Devine   +4 more
doaj   +1 more source

Condotte compulsive in paziente con sindrome di Aicardi. agenesia del corpo calloso [PDF]

, 2013
The corpus callosum, which is the largest white matter structure in the brain of all placental mammals, connects the left and right cerebral hemispheres.
A. Anastasia, A. Quartini, BERSANI, Giuseppe, C. Colletti, E. Prinzivalli, F. S. Bersani, G. Valeriani   +6 more
core  

Protein structure and phenotypic analysis of pathogenic and population missense variants in STXBP1 [PDF]

, 2017
Background: Syntaxin-binding protein 1, encoded by STXBP1, is highly expressed in the brain and involved in fusing synaptic vesicles with the plasma membrane.
Baker, K, Clayton-Smith, J, Dabir, T, DDD Study, Evers, JMG, Josifova, D, Joss, S, Kerr, B, Kraus, A, Laskowski, RA, McEntagart, M, Morton, J, O'Brien, S, Smith, A, Splitt, M, Suri, M, Thornton, JM, Wright, CF   +17 more
core   +2 more sources