Results 111 to 120 of about 7,251,989 (335)

The two-type Richardson model with unbounded initial configurations

open access: yes, 2007
The two-type Richardson model describes the growth of two competing infections on $\mathbb{Z}^d$ and the main question is whether both infection types can simultaneously grow to occupy infinite parts of $\mathbb{Z}^d$. For bounded initial configurations,
Deijfen, Maria, Häggström, Olle
core   +2 more sources

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

open access: yesMolecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li   +12 more
wiley   +1 more source

Effects of co-infection on the clinical outcomes of Clostridium difficile infection [PDF]

open access: yes, 2020
Background: Clostridium difficile (C. difficile) is a spore-forming, Gram-positive rod that is known to be associated with antibiotic use. It is one of the leading causes of nosocomial diarrhea in the industrialized world and therefore warrants further ...
Alturkmani, Hani   +6 more
core   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

open access: yesMolecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza   +3 more
wiley   +1 more source

Salmonella Infection After Craniotomy. [PDF]

open access: yes, 2017
Salmonella is an uncommon cause of meningitis, especially after neurosurgery. Here, we present a case of Salmonella meningitis after craniotomy, likely due to physical contact with a snake after surgery, with contiguous spread from the patient's hand to ...
Byer, Lennox   +5 more
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Neurosyphilis Presenting as Sleep Disorder and Muscle Soreness Complicated With HIV Infection: A Case Report

open access: yesCase Reports in Infectious Diseases
Neurosyphilis is a tertiary syphilis complication or manifestation caused by Treponema pallidum, which invades the central nervous system. Its clinical manifestations are often nonspecific.
Shu-Qi Yang   +5 more
doaj   +1 more source

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