Results 71 to 80 of about 12,800,706 (262)

Infection control measures in response to detection of carbapenem-resistant enterobacterales in neonatal intensive care unit

Antimicrobial Stewardship & Healthcare Epidemiology
Objectives: Neonatal intensive care unit (NICU) admits premature babies and neonates with acute illness who are under high infection risk due to immature immune response system.
Hee Jeong Wang, Ji Yeoung Yim, Na Yoon Kim, Go Eun Kim, Ji Eun Park, Yun Ah Choi, Seo Young Yoo, Young Hwa Choi, Hyun Joo Jung   +8 more
doaj   +1 more source

Babesia spp. and other pathogens in ticks recovered from domestic dogs in Denmark

Parasites & Vectors, 2015
Background Newly recognized endemic foci for human babesiosis include Europe, where Ixodes ricinus, a vector for several species of Babesia, is the most commonly identified tick.
Christen Rune Stensvold, Dua Al Marai, Lee O’Brien Andersen, Karen Angeliki Krogfelt, Jørgen Skov Jensen, Kim Søholt Larsen, Henrik Vedel Nielsen   +6 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Infection control in Switzerland

, 1995
Infection control in hospitals is not mandatory in Switzerland as in the United States. There are more than 300 acute-care hospitals in Switzerland. Hospitals are reimbursed by patient-days rather than diagnosis-related group.
Pittet, Didier, Ruef, C., Francioli, Patrick, Widmer, A. F., Widmer, A. F., Raeber, P. A., von Overbeck, J., Pittet, D., Francioli, P., Raeber, P. A., Ruef, Christian, von Overbeck, J.   +11 more
core   +1 more source

Prognostic Value of MicroRNA Profiles in Septic Patients with Rare Hereditary Anemias: Insights from a Longitudinal Cohort Study

International Journal of General Medicine
May AlMoshary,1,2 Nahid Abdulhamid Qushmaq,3 Abba Elgujja,4 Abdullah Mikki Alamoudi,4 Maha Abuhatlah AlQahtani,4 Hind Bugshan,4 Marytonia Valiyaveettil Antony,4 Fatimah Alshahrani3– 5 1Hematology and Transfusion Medicine, Department of Basic Science ...
AlMoshary M, Qushmaq NA, Elgujja A, Alamoudi AM, AlQahtani MA, Bugshan H, Antony MV, Alshahrani F   +7 more
doaj  

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Impact of International Nosocomial Infection Control Consortium (INICC) Strategy on Central Line-Associated Bloodstream Infection Rates in the Intensive Care Units of 15 Developing Countries [PDF]

, 2010
BACKGROUND. the International Nosocomial Infection Control Consortium (INICC) was established in 15 developing countries to reduce infection rates in resource-limited hospitals by focusing on education and feedback of outcome surveillance (infection ...
Maki, Dennis George, Alvarez-Moreno, Carlos, Madani, Naoufel, Int Nosocomial Infect Control, Dennis G. Maki, Carlos Álvarez-Moreno, Zan Mitrev, Álvarez-Moreno, Carlos Arturo, Cuellar, Luis E., Rodrigues, Camila, Victor D. Rosenthal, Luis E. Cuéllar, Rosalía Fernández-Hidalgo, Mitrev, Zan, Eduardo A. Medeiros, Leblebicioglu, Hakan, Guanche-Garcell, Humberto, Regina Berba, Naoufel Madani, Medeiros, Eduardo A. [UNIFESP], Berba, Regina, Trudell Mapp, Hakan Leblebicioglu, Martha Sobreyra-Oropeza, Lourdes Dueñas, Rosenthal, Víctor Daniel, Fernandez-Hidalgo, Rosalia, Camila Rodrigues, Medeiros, Eduardo A., Sobreyra-Oropeza, Martha, Humberto Guanche-Garcell, Duenas, Lourdes, Souha S. Kanj, Mapp, Trudell, null null, Kanj, Souha S., Rosenthal, Victor D., Maki, Dennis G., International Nosocomial Infection Control Consortium Investigators   +38 more
core   +1 more source