Results 81 to 90 of about 12,800,706 (262)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Infection prevention and control assessment tool for acute care hospitals [PDF]

Version 1.3.2 SEPT 2016This tool is intended to assist in the assessment of infection control programs and practices in acute care hospitals. If feasible, direct observations of infection control practices are encouraged.

core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Infection prevention and control measures for emerging infectious disease: lessons learned from the first case of imported Lassa fever in China

Antimicrobial Resistance and Infection Control
Background Lassa fever is an acute viral hemorrhagic disease prevalent in West Africa. West China Hospital of Sichuan University (WCHSCU) received China’s first imported case of Lassa fever from overseas.
Yalan Peng, Yantong Wang, Shiyu Li, Jing Huang, Wu Shi, Ruocheng Luo, Xianmou Pan, Wenzhi Huang, Fu Qiao, Yi Chen   +9 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Infection control in healthcare personnel : infrastructure and routine practices for occupational infection prevention and control services [PDF]

Updated: October 2019This document, Infection Control in Healthcare Personnel: Infrastructure and Routine Practices for Occupational Infection Prevention and Control Services, is an update of four sections of Part I of the Guideline for infection control

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A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Paramedic knowledge of infection control principles and standards in an Australian emergency medical system (EMS)

, 2006
Griffith Health, School of Nursing and MidwiferyNo Full ...
Shaban, Ramon Z
core  

Surgical site infection prevention in Gynae-oncology unit: together we can

Antimicrobial Stewardship & Healthcare Epidemiology
Objective: To describe a collaboration effort between gynae-oncology and infection control unit in a sustainable surgical side infection prevention program Methods: In January 2023, gynae-oncologist noted a surge in surgical side infection (SSI) in gynae-
Ke Juin Wong, Suguna A/P Subramanian, Maria Limjoon, Cynthi Christie Anthony, Prisca Masiry, Siew Moy Fong   +5 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source