Results 101 to 110 of about 2,365,736 (349)

The Cancer Transition in Japan since 1951 [PDF]

open access: yes
The overall trend of cancer mortality in Japan has been decreasing since the 1960s (age-standardized death rates for ages 30-69), though trends differ enormously among various forms of the disease.
John R. Wilmoth, Omer Gersten
core  

Factors Associated with Health Inequalities in Infectious Disease Pandemics Predating COVID-19 in the United States: A Systematic Review

open access: gold, 2022
Karli Kondo   +7 more
openalex   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

INFECTIOUS DISEASE, DEVELOPMENT, AND CLIMATE CHANGE: A SCENARIO ANALYSIS [PDF]

open access: yes
We study the effects of development and climate change on infectious disease in Sub-Saharan Africa. Infant mortality and infectious disease are close related, but there are better data for the former. In an international cross-section, per capita income,
Gary W. Yohe   +2 more
core  

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

Front Matter

open access: yesIndonesian Journal of Tropical and Infectious Disease, 2020
Indonesian Journal of Tropical and Infectious Disease
doaj   +1 more source

Screening of drug targets for tuberculosis on the basis of transcription factor regulatory network and mRNA sequencing technology

open access: yesFrontiers in Molecular Biosciences
BackgroundTuberculosis is a worldwide epidemic disease, posing a serious threat to human health. To find effective drug action targets for Mycobacterium tuberculosis, differentially expressed genes in tuberculosis patients and healthy people were ...
Shuai Wang   +6 more
doaj   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Back Matter

open access: yesIndonesian Journal of Tropical and Infectious Disease, 2020
Indonesian Journal of Tropical and Infectious Disease
doaj   +1 more source

IL-33-Pretreated Mesenchymal Stem Cells Attenuate Acute Liver Failure by Improving Homing and Polarizing M2 Macrophages

open access: yesStem Cells International
Mesenchymal stem cells (MSCs) are highly effective in the treatment of acute liver failure (ALF). The efficacy of MSCs is closely related to the inflammatory environment.
Hui Yuan   +9 more
doaj   +1 more source

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