Results 41 to 50 of about 326,517 (248)

Refining Coarse-grained Spatial Data using Auxiliary Spatial Data Sets with Various Granularities

, 2019
We propose a probabilistic model for refining coarse-grained spatial data by utilizing auxiliary spatial data sets. Existing methods require that the spatial granularities of the auxiliary data sets are the same as the desired granularity of target data.
Iwata, Tomoharu, Kurashima, Takeshi, Okawa, Maya, Tanaka, Toshiyuki, Tanaka, Yusuke, Toda, Hiroyuki   +5 more
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

SpaGraphCCI: Spatial cell–cell communication inference through GAT‐based co‐convolutional feature integration

IET Systems Biology
Spatially resolved transcriptomics technologies potentially provide the extra spatial position information and tissue image to better infer spatial cell–cell interactions (CCIs) in processes such as tissue homeostasis, development, and disease ...
Han Zhang, Ting Cui, Xiaoqiang Xu, Guangyu Sui, Qiaoli Fang, Guanghao Yang, Yizhen Gong, Sanqiao Yang, Yufei Lv, Desi Shang   +9 more
doaj   +1 more source

Higher-Order Conditioning in the Spatial Domain

Frontiers in Behavioral Neuroscience, 2021
Spatial learning and memory, the processes through which a wide range of living organisms encode, compute, and retrieve information from their environment to perform goal-directed navigation, has been systematically investigated since the early twentieth
Youcef Bouchekioua, Yutaka Kosaki, Shigeru Watanabe, Aaron P. Blaisdell   +3 more
doaj   +1 more source

Spatial modeling of extreme snow depth

, 2011
The spatial modeling of extreme snow is important for adequate risk management in Alpine and high altitude countries. A natural approach to such modeling is through the theory of max-stable processes, an infinite-dimensional extension of multivariate ...
Blanchet, Juliette, Davison, Anthony C.
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Local rabies transmission and regional spatial coupling in European foxes.

PLoS ONE, 2020
Infectious diseases are often transmitted through local interactions. Yet, both surveillance and control measures are implemented within administrative units.
Laurie Baker, Jason Matthiopoulos, Thomas Müller, Conrad Freuling, Katie Hampson   +4 more
doaj   +1 more source

Inferring ASF transmission in domestic pigs and wild boars using a paired model iterative approach

Epidemics, 2023
The rapid spread of African swine fever (ASF) in recent years has once again raised awareness of the need to improve our preparedness in preventing and managing outbreaks, for which modelling-based forecasts can play an important role.
G. Beaunée, F. Deslandes, E. Vergu
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source