Results 21 to 30 of about 51,069 (251)

How to Make AlphaGo’s Children Explainable

open access: yesPhilosophies, 2022
Under the rubric of understanding the problem of explainability of AI in terms of abductive cognition, I propose to review the lessons from AlphaGo and her more powerful successors.
Woosuk Park
doaj   +1 more source

Naturalizing Logic: How Knowledge of Mechanisms Enhances Inductive Inference

open access: yesPhilosophies, 2021
This paper naturalizes inductive inference by showing how scientific knowledge of real mechanisms provides large benefits to it. I show how knowledge about mechanisms contributes to generalization, inference to the best explanation, causal inference, and
Paul Thagard
doaj   +1 more source

Inference to the best action and its basis in clinical expertise

open access: yesFrontiers in Psychology, 2023
Can contemporary cognitive science explain clinical expertise? We argue that the answer could be “no.” In support of this, we provide an analysis of two of the most essential expressions of clinical expertise in nursing and medicine, the ability to run a
Mark Fedyk   +3 more
doaj   +1 more source

Induction, deduction and inference to the best explanation

open access: yesFilosofia Unisinos, 2021
Starting from the concept of abduction coined by Pierce, Harman, Josephson and Psillos have recently claimed that inference to the best explanation is the scientific method par excellence and favour a realist conception of scientific theories.
Rodolfo Gaeta
doaj  

Methods of Inference and Shaken Baby Syndrome

open access: yesPhilosophy of Medicine, 2023
Exploring the early development of an area of medical literature can inform contemporary medical debates. Different methods of inference include deduction, induction, abduction, and inference to the best explanation.
Nicholas Binney
doaj   +1 more source

Analogies and Other Minds

open access: yesInformal Logic, 2009
The argument by analogy for other minds is customarily rejected as a weak inference because the argument is based on a single instance. The current paper argues that this objection  fundamentally misunderstands the inferential structure of analogies and ...
Bryan Benham
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

K roli abdukce v právním myšlení aneb jak poznatky o abdukci mohou zvýšit pro-systémovost interpretace a aplikace práva

open access: yesActa Universitatis Carolinae Iuridica, 2019
The paper deals with the issue of abduction. First of all, the paper presents the development of the concept of abduction in the work of Charles S. Peirce, who was the first in modern history to examine abduction and suggested its two partially different
Katarzyna Žák Krzyžanková
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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