Results 31 to 40 of about 12,808 (176)

Association Characteristics and Potential Mechanisms of Aging, Gut Microbiota, and Hearing Loss

Integrative Zoology, EarlyView.
The study found that aging leads to unchanged gut microbiota alpha diversity but an increase in Bacteroidetes and a decrease in Firmicutes at the phylum level, with specific genera, species, and functional pathways co‐associated with aging and hearing loss. Through constructing a microbe‐metabolite network, it revealed the mechanism by which protective
Cheng Cheng, Lu Wang, Runhan Li, Wenkai Lai, Chongkui Sun, Jianguo Cui, Bicheng Zhu, Jiang Zhang   +7 more
wiley   +1 more source

Patterns of convergence in the central nucleus of the inferior colliculus of the Mongolian gerbil: organization of inputs from the superior olivary complex in the low frequency representation

Frontiers in Neural Circuits, 2013
Projections to the inferior colliculus from the lateral and medial superior olivary nuclei were studied in the gerbil (Meriones unguiculatus) with neuroanatomical tract-tracing methods. The terminal fields of projecting axons were labeled via anterograde
Nell B Cant
doaj   +1 more source

Amylin analogues as a novel perspective in anti‐obesity therapy

British Journal of Pharmacology, EarlyView.
Abstract Public health systems face a major challenge because of the worldwide obesity epidemic. The number of obese individuals has increased dramatically and, even in Switzerland which may be considered a relatively “lean” country, the numbers are alarmingly high and have reached almost 50% of the adult population.
Thomas A. Lutz
wiley   +1 more source

Muscarinic agonists for schizophrenia: Bridging preclinical evidence and clinical enthusiasm

British Journal of Pharmacology, EarlyView.
Abstract Antipsychotic drugs targeting dopamine receptors have been used to treat schizophrenia for decades, primarily alleviating positive symptoms such as hallucinations and delusions. However, they provide limited benefit for cognitive and negative symptoms—major contributors to poor outcomes—and are frequently associated with significant side ...
Brian J. Morris, Judith A. Pratt
wiley   +1 more source

Microvascular organization of the cat inferior colliculus [PDF]

Hearing Research, 2011
Brain neural activity depends critically on the blood supply to a given structure. The blood supply can differ within and between divisions, which may have functional significance. We analyzed the microvascular organization of the cat inferior colliculus (IC) to determine if the capillary distribution is homogenous throughout.
Yohan, Song, Jeffrey G, Mellott, Jeffery A, Winer   +2 more
openaire   +2 more sources

Seizure Susceptibility Corrupts Inferior Colliculus Acoustic Integration

Frontiers in Systems Neuroscience, 2019
Evidence suggests that the pathophysiology associated with epileptic susceptibility may disturb the functional connectivity of neural circuits and compromise the brain functions, even when seizures are absent.
Hyorrana Priscila Pereira Pinto, Eric Levi de Oliveira Lucas, Vinícius Rezende Carvalho, Vinícius Rezende Carvalho, Flávio Afonso Gonçalves Mourão, Flávio Afonso Gonçalves Mourão, Leonardo de Oliveira Guarnieri, Leonardo de Oliveira Guarnieri, Eduardo Mazoni Andrade Marçal Mendes, Daniel de Castro Medeiros, Daniel de Castro Medeiros, Márcio Flávio Dutra Moraes, Márcio Flávio Dutra Moraes   +12 more
doaj   +1 more source

Synaptic mechanisms of top-down control in the non-lemniscal inferior colliculus

eLife, 2022
Corticofugal projections to evolutionarily ancient, subcortical structures are ubiquitous across mammalian sensory systems. These ‘descending’ pathways enable the neocortex to control ascending sensory representations in a predictive or feedback manner ...
Hannah M Oberle, Alexander N Ford, Deepak Dileepkumar, Jordyn Czarny, Pierre F Apostolides   +4 more
doaj   +1 more source

Neonatal Assessment Visual European Grid accuracy in detecting infants born preterm at risk of neurological impairment

Developmental Medicine &Child Neurology, EarlyView.
NAVEG: a screening tool for detecting preterm newborn at risk of neurolocal impairment, key findings and diagnostic accuracy. Abstract Aim To analyse the factorial structure of the Neonatal Assessment Visual European Grid (NAVEG), its diagnostic accuracy, the discriminative capacity of its individual items, and total score in detecting infants born ...
Elisa Fazzi, Laura Malerba, Jessica Galli, Salvatore Aversa, Lotfi B. Merabet, Francesco Risso, Andrea Rossi, NAVEG Group, Patrizia Accorsi, Anna Alessandrini, Sabina Bettelli, Nicole D'adda, Erika Loi, Michela Gritti, Paola Martelli, Paola Mattei, Giuseppe Nascimbeni, Federica Tansini, Francesco Semeraro, Vania Spinoni, Serena Micheletti, Giulia Balboni   +21 more
wiley   +1 more source

Sound offset responses become highly informative in the auditory cortex

The Journal of Physiology, EarlyView.
Abstract figure legend Using large datasets of neural responses to diverse sounds recorded across four stages of the mouse auditory system (depicted and colour‐coded on the left), offset responses occurring after the termination of each sound (time window indicated by the orange shaded area superimposed with activity traces) were characterized and it ...
Charly Lamothe, Sophie Bagur, Etienne Gosselin, Brice Bathellier   +3 more
wiley   +1 more source

Temporal Expression of Wnt1 Defines the Competency State and Terminal Identity of Progenitors in the Developing Cochlear Nucleus and Inferior Colliculus

Frontiers in Neuroanatomy, 2017
The auditory system contains a diverse array of interconnected anatomical structures that mediate the perception of sound. The cochlear nucleus of the hindbrain serves as the initial site of convergence for auditory stimuli, while the inferior colliculus
Stephen Brown, Mark Zervas, Mark Zervas, Mark Zervas   +3 more
doaj   +1 more source