Results 51 to 60 of about 12,808 (176)

Longitudinal Tracking of Astrocyte Reactivity During the Development of Chronic Orofacial Neuropathic Pain Using [18F]‐SMBT‐1 Positron‐Emission Tomography

Glia, Volume 74, Issue 8, August 2026.
Using [18F]‐SMBT‐1 PET, we longitudinally tracked MAO‐B–expressing reactive astrocytes during orofacial neuropathic pain development in rats, revealing region‐ and time‐specific astrocyte activation during pain chronification. ABSTRACT Chronic neuropathic pain represents a significant global health burden and is hypothesized to be maintained by an ...
Lewis S. Crawford, James W. M. Kang, OIivia I. Davanzo, Hyunsol Lim, Sabrina Salberg, Marissa Srgo, Crystal Li, Gaelle M. Emvalomenos, Bianca Jupp, Matthew Long, Wayne Noonan, Mohammad B. Haskali, Richelle Mychasiuk, Kevin A. Keay, Luke A. Henderson   +14 more
wiley   +1 more source

Primary Age-Related Tauopathy in Human Subcortical Nuclei

Frontiers in Neuroscience, 2019
The present study aimed to determine the spatial distribution patterns of hyperphosphorylated tau-immunoreactive cells in subcortical nuclei of post-mortem human brain with primary age-related tauopathy (PART).
Keqing Zhu, Keqing Zhu, Xin Wang, Xin Wang, Bing Sun, Juanli Wu, Hui Lu, Xiaoling Zhang, Huazheng Liang, Huazheng Liang, Dandan Zhang, Chong Liu, Chong Liu   +12 more
doaj   +1 more source

Reducing Inhomogeneous MT (ihMT) Acquisition Time Using Frequency Alternation at Low Duty Cycle for Single Offset (FALSO) MT Preparations

Magnetic Resonance in Medicine, Volume 96, Issue 1, Page 191-202, July 2026.
ABSTRACT Purpose To evaluate Frequency Alternation at Low duty cycle for Single Offset (FALSO) as a novel Magnetization Transfer (MT) preparation scheme to increase speed and/or spatial resolution of inhomogeneous MT (ihMT) MRI by reducing the number of volumes required.
Gopal Varma, Aaron K. Grant, Lucas Soustelle, Olivier M. Girard, Guillaume Duhamel, David C. Alsop   +5 more
wiley   +1 more source

Creation of an MRI‐Based Three‐Dimensional Common Wombat (Vombatus ursinus) Brain Atlas and Linking Brain Morphometry to Wombat Behaviour

Anatomia, Histologia, Embryologia, Volume 55, Issue 4, July 2026.
ABSTRACT Marsupials lack a corpus callosum; in its place Diprodontia have a fasciculus aberrans connecting the hemispheres. However, despite this uniqueness, the realm of marsupial brain anatomy remains largely unexplored, especially through the lens of modern imaging techniques.
Natasha B. Anthoniel, Kristy R. Q. Goh, Timothy J. Stait‐Gardner, Nyoman D. Kurniawan, Marianne D. Keller   +4 more
wiley   +1 more source

Effect of Electroacupuncture on Expression of Catechol-O-methyltransferase in the Inferior Colliculus and Auditory Cortex in Age-related Hearing Loss Guinea Pigs

针刺研究, 2017
Objective To observe the expression of catechol-O-methyltransferase(COMT)in inferior colliculus and auditory cortex of guinea pigs with age-related hearing loss(AHL)induced by D-galactose,so as to explore the possible mechanism of electroacupuncture(EA ...
LIU Shu-yun, DENG Li-qiang, YANG Ye, YIN Ze-deng   +3 more
doaj  

Electrophysiological Recording With Activated Iridium Oxide: Effective Electrode Area, Not Total Impedance, Determines Performance

European Journal of Neuroscience, Volume 64, Issue 2, July 2026.
Linear diffusion electroactive area determines the number of neurons within recording distance of an implanted electrode, impacting signal‐to‐noise ratio and spike count. Impedance measurements are mainly of benefit as an indirect measure of electrode area.
Alexander R. Harris, Ben J. Allitt, Antonio G. Paolini   +2 more
wiley   +1 more source

Auditory Hyperresponsivity in Chronic Back Pain: A Randomized Controlled Trial of Pain Reprocessing Therapy

Annals of Neurology, Volume 99, Issue 6, Page 1555-1567, June 2026.
Objective Heightened sensitivity to noxious stimulation is a hallmark of chronic pain. Emerging evidence suggests heightened unpleasantness to non‐noxious (eg, auditory) aversive stimulation also characterizes chronic pain, but its magnitude, neural mechanisms, and treatment modifiability remain unknown.
Alina E. C. Panzel, Christian Büchel, Andrew Leroux, Tor D. Wager, Yoni K. Ashar   +4 more
wiley   +1 more source

Transcranial Calcium Macro‐Imaging From the Auditory Cortex of Thy1‐Cre‐Driven GCaMP8 Transgenic Rats

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
We generated Thy1‐Cre–driven GCaMP8 transgenic rats by mating Thy1‐Cre rats with knock‐in rats carrying a floxed GCaMP8‐STOP cassette in the β‐actin locus. Robust neuronal GCaMP8 expression enabled transcranial calcium imaging of the auditory cortex, establishing this model as a powerful tool for minimally invasive cortical macro‐imaging and functional
Manavu Tohmi, Hisaaki Namba, Meiko Kawamura, Ryuichi Hishida, Shota Iguchi, Kazuto Kobayashi, Natsuki Matsushita, Tomoji Mashimo, Rie Natsume, Kenji Sakimura, Hiroyuki Nawa   +10 more
wiley   +1 more source

Pharmacologic MRI Brain Imaging Studies of Serotonin 5‐HT1 Receptor Agonists in Awake Mice

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Serotonin (5‐hydroxytryptamine, 5‐HT) type‐1 G protein‐coupled receptors are expressed throughout the central nervous system. 5‐HT1AR activation is the putative mechanism of approved drugs for generalized anxiety disorder and major depressive disorder and is being studied in the treatment of autism and neurological disorders.
Brittany M. Brems, Erin E. Sullivan, Ryan P. McGlynn, Praveen Kulkarni, Craig F. Ferris, Raymond G. Booth   +5 more
wiley   +1 more source

Intracellular responses to frequency modulated tones in the dorsal cortex of the mouse inferior colliculus

Frontiers in Neural Circuits, 2013
Frequency modulations occur in many natural sounds, including vocalizations. The neuronal response to frequency modulated (FM) stimuli has been studied extensively in different brain areas, with an emphasis on the auditory cortex and the central nucleus ...
Ruediger eGeis, Gerard eBorst
doaj   +1 more source