Aperiodic rhythms of the inferior olive
PLOS Computational Biology, 2018 Inferior olivary activity causes both short-term and long-term changes in cerebellar output underlying motor adaptation and motor learning, respectively. Many of its neurons engage in coherent subthreshold oscillations and are extensively coupled via gap
P. Warnaar +8 more
semanticscholar +6 more sources
The Superior Colliculus Projection Upon the Macaque Inferior Olive
Brain Structure and Function, 2023 Saccade accommodation is a productive model for exploring the role of the cerebellum in behavioral plasticity. In this model, the target is moved during the saccade, gradually inducing a change in the saccade vector as the animal adapts.
P. May, S. Warren, Y. Kojima
semanticscholar +4 more sources
Delayed Complex Spike Response Evoked by Conditioned Stimulus Encodes Movement Onset Time and Is Determined by Intrinsic Inferior Olive Properties [PDF]
Frontiers in Systems Neuroscience, 2019 Recent studies demonstrate that after classical conditioning the conditioned stimulus (CS) triggers a delayed complex spike. This new finding revolutionizes our view on the role of complex spike activity.
Yasmin Yarden-Rabinowitz +3 more
doaj +2 more sources
Effects of inferior olive lesion on fear-conditioned bradycardia. [PDF]
Neuroreport, 2014 The inferior olive (IO) sends excitatory inputs to the cerebellar cortex and cerebellar nuclei through the climbing fibers. In eyeblink conditioning, a model of motor learning, the inactivation of or a lesion in the IO impairs the acquisition or ...
Kotajima H +3 more
europepmc +2 more sources
Imaging Subthreshold Voltage Oscillation With Cellular Resolution in the Inferior Olive in vitro [PDF]
Frontiers in Cellular Neuroscience, 2020 Voltage imaging with cellular resolution in mammalian brain slices is still a challenging task. Here, we describe and validate a method for delivery of the voltage-sensitive dye ANNINE-6plus (A6+) into tissue for voltage imaging that results in higher ...
Kevin Dorgans +2 more
doaj +2 more sources
Using subthreshold events to characterize the functional architecture of the electrically coupled inferior olive network [PDF]
eLife, 2020 The electrical connectivity in the inferior olive (IO) nucleus plays an important role in generating well-timed spiking activity. Here we combined electrophysiological and computational approaches to assess the functional organization of the IO nucleus ...
Yaara Lefler +4 more
doaj +2 more sources
Synchronicity and Rhythmicity of Purkinje Cell Firing during Generalized Spike-and-Wave Discharges in a Natural Mouse Model of Absence Epilepsy [PDF]
Frontiers in Cellular Neuroscience, 2017 Absence epilepsy is characterized by the occurrence of generalized spike and wave discharges (GSWDs) in electrocorticographical (ECoG) recordings representing oscillatory activity in thalamocortical networks.
Lieke Kros +9 more
doaj +8 more sources
Frontiers in Computational Neuroscience, 2014 The cerebellum is known to play a critical role in learning relevant patterns of activity for adaptive motor control, but the underlying network mechanisms are only partly understood.
Niceto Rafael Luque +6 more
doaj +2 more sources
Impaired Motor Learning in a Disorder of the Inferior Olive: Is the Cerebellum Confused? [PDF]
Cerebellum, 2017 Shaikh AG, Wong AL, Optican LM, Zee DS.
europepmc +3 more sources
Frontocerebellar connectivity: climbing through the inferior olive [PDF]
Frontiers in Neuroscience, 2010 Is there a role of cerebellum beyond motor control? Neuroanatomical studies in non-human primates have shown connections between the cerebellum and non-motor cortical areas of the frontal lobe (Strick et al., 2009). These studies have not only supported the theoretical framework of how the cerebellum is involved in motor control but also forward models
Rui M Costa +4 more
doaj +4 more sources