Results 211 to 220 of about 172,040 (288)

Pharmacological Effects and Immune Mechanisms of Oriental Medicines in Restoring Male Infertility. [PDF]

Int J Mol Sci
Qu N.
europepmc   +1 more source

Neuronal FGF13 Inhibits Mitochondria‐Derived Damage Signals to Prevent Neuroinflammation and Neurodegeneration in a Mouse Model of Parkinson's Disease

Advanced Science, EarlyView.
This study elucidates a novel role of FGF13 in manipulating neuronal fate via mitochondrial transfer. FGF13 is identified as a mitochondria‐stabilizing protein by interacting with mitochondrial proteins. Under stress, the decrease of neuronal FGF13 fails to retain mitochondria within the cytoplasm, leading to the release of damaged mitochondria to ...
Nanshan Song, Xiangxu Wang, Luqing Ha, Lamei Hu, Shuyuan Mei, Yue Liang, Yujie Zhao, Xingyin Yang, Qingyu Zhang, Yuanzhang Zhou, Jianhua Ding, Yan Liu, Qigang Zhou, Feng Han, Gang Hu, Ming Lu   +15 more
wiley   +1 more source

Development of a single-center predictive model for conventional in vitro fertilization outcomes excluding total fertilization failure: implications for protocol selection. [PDF]

J Ovarian Res
Wang H, Pan H, Xu Z, Zheng X, Xia S, Zheng J.   +5 more
europepmc   +1 more source

Refractive Index‐Corrected Light‐Sheet Microscopy for Macro‐View Cardiovascular Imaging

Advanced Science, EarlyView.
A refractive index‐corrected light‐sheet fluorescence microscopy system enables macro‐view cardiovascular imaging across organs, adapting to refractive index variations from different optical clearing protocols. By integrating axial sweeping, multi‐view imaging, and a sealed chamber, it extends the field of view, enhances isotropy, and improves safety.
Enbo Zhu, Yaran Zhang, Peng Zhao, Jae Min Cho, Zhaoqiang Wang, Yan‐Ruide Li, Jing Wang, Samuel Margolis, Shaolei Wang, Lili Yang, Alison Chu, Yuhua Zhang, Liang Gao, Tzung K. Hsiai   +13 more
wiley   +1 more source

Dietary and Lifestyle Interventions to Mitigate Oxidative Stress in Male and Female Fertility: Practical Insights for Infertility Management-A Narrative Review. [PDF]

Metabolites
Moustakli E, Zikopoulos A, Katopodis P, Dafopoulos S, Paraschos VS, Zachariou A, Dafopoulos K.   +6 more
europepmc   +1 more source

In Situ Programming of the Tumor Microenvironment to Alleviate Immunosuppression for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
cmExoaCD11b induced the repolarization of immunosuppressive M2 macrophages into pro‐inflammatory M1 phenotype, thereby promoting the proliferation and activation of CD8+ T cells and reversing the immunosuppressive state of the tumor microenvironment.
Man Sun, Huan Zhang, Yarui Ma, Simiao Wang, Jiayi Chen, Yaxin Cui, Yun Zhang, Siyuan Hu, Dan Zhou, Pengchen Zhang, Yahui Liu, Betty Y.S. Kim, Wen Jiang, Xiaobing Wang, Zhaogang Yang   +14 more
wiley   +1 more source

Reproductive Health and Assisted Conception in Celiac Disease and Non-Celiac Gluten Sensitivity: A Narrative Review. [PDF]

Nutrients
Moustakli E, Christopoulos P, Potiris A, Zikopoulos A, Drakaki E, Karampitsakos T, Anagnostaki I, Kathopoulis N, Katopodis P, Galani A, Christodoulaki C, Zachariou A, Drakakis P, Stavros S.   +13 more
europepmc   +1 more source

BCG‐Derived Outer Membrane Vesicles Induce TLR2‐Dependent Trained Immunity to Protect Against Polymicrobial Sepsis

Advanced Science, EarlyView.
B‐OMVs, nanoscale vesicles derived from BCG, are identified as effective and safe inducers of trained immunity that protect against sepsis. Through TLR2‐mediated metabolic and epigenetic reprogramming of hematopoietic stem cells, B‐OMVs enhance inflammatory response and phagocytic activity.
Yuan Gong, Wenyan Hao, Lingqi Xu, Yingyi Yang, Zhenzhen Dong, Peng Pan, Zhenjiang Bai, Jie Huang, Kaidi Yang, Zhu Jin, Rui Kang, Qiang Shan, Jiang huai Wang, Zijian Zhou, Daolin Tang, Jian Wang, Huiting Zhou   +16 more
wiley   +1 more source

Retraction of Deficient LRRC8A-dependent volume-regulated anion channel activity is associated with male infertility in mice. [PDF]

JCI Insight
Bao J, Perez CJ, Kim J, Zhang H, Murphy CJ, Hamidi T, Jaubert J, Platt CD, Chou J, Deng M, Zhou MH, Huang Y, Gaitán-Peñas H, Guénet JL, Lin K, Lu Y, Chen T, Bedford MT, Dent SY, Richburg JH, Estévez R, Pan HL, Geha RS, Shi Q, Benavides F.   +24 more
europepmc   +1 more source

Delayed Transplantation of Neural Stem Cells Improves Initial Graft Survival after Stroke

Advanced Science, EarlyView.
Delayed transplantation of human iPSC‐derived neural progenitor cells (NPCs) enhances graft survival, proliferation, and axonal sprouting after stroke. Using bioluminescence imaging and histology in a mouse model of stroke, it is shown that NPC delivery at 7 days post‐stroke is more effective than acute transplantation, highlighting the importance of ...
Rebecca Z Weber, Nora H Rentsch, Beatriz Achón Buil, Melanie Generali, Lina R. Nih, Christian Tackenberg, Ruslan Rust   +6 more
wiley   +1 more source