Data-Driven Prediction of Embryo Implantation Probability Using IVF Time-lapse Imaging [PDF]
The process of fertilizing a human egg outside the body in order to help those suffering from infertility to conceive is known as in vitro fertilization (IVF). Despite being the most effective method of assisted reproductive technology (ART), the average success rate of IVF is a mere 20-40%.
arxiv
Reduced model for female endocrine dynamics: Validation and functional variations [PDF]
A normally functioning menstrual cycle requires significant crosstalk between hormones originating in ovarian and brain tissues. Reproductive hormone dysregulation may cause abnormal function and sometimes infertility. The inherent complexity in this endocrine system is a challenge to identifying mechanisms of cycle disruption, particularly given the ...
arxiv
We introduce tools from discrete convexity theory and polyhedral geometry into the theory of West's stack-sorting map $s$. Associated to each permutation $\pi$ is a particular set $\mathcal V(\pi)$ of integer compositions that appears in a formula for the fertility of $\pi$, which is defined to be $|s^{-1}(\pi)|$.
arxiv
Exact Reasoning Under Uncertainty [PDF]
This paper focuses on designing expert systems to support decision making in complex, uncertain environments. In this context, our research indicates that strictly probabilistic representations, which enable the use of decision-theoretic reasoning, are highly preferable to recently proposed alternatives (e.g., fuzzy set theory and Dempster-Shafer ...
arxiv
A Survey of Semen Quality Evaluation in Microscopic Videos Using Computer Assisted Sperm Analysis [PDF]
The Computer Assisted Sperm Analysis (CASA) plays a crucial role in male reproductive health diagnosis and Infertility treatment. With the development of the computer industry in recent years, a great of accurate algorithms are proposed. With the assistance of those novel algorithms, it is possible for CASA to achieve a faster and higher quality result.
arxiv
Towards deep learning-powered IVF: A large public benchmark for morphokinetic parameter prediction [PDF]
An important limitation to the development of Artificial Intelligence (AI)-based solutions for In Vitro Fertilization (IVF) is the absence of a public reference benchmark to train and evaluate deep learning (DL) models. In this work, we describe a fully annotated dataset of 704 videos of developing embryos, for a total of 337k images. We applied ResNet,
arxiv
A high-throughput analysis of ovarian cycle disruption by mixtures of aromatase inhibitors [PDF]
Background: Combining computational toxicology with ExpoCast exposure estimates and ToxCast assay data gives us access to predictions of human health risks stemming from exposures to chemical mixtures. Objectives: To explore, through mathematical modeling and simulations, the size of potential effects of random mixtures of aromatase inhibitors on ...
arxiv
Evaluating the Feasibility and Accuracy of Large Language Models for Medical History-Taking in Obstetrics and Gynecology [PDF]
Effective physician-patient communications in pre-diagnostic environments, and most specifically in complex and sensitive medical areas such as infertility, are critical but consume a lot of time and, therefore, cause clinic workflows to become inefficient.
arxiv
Numerical constraints on the size of generation ships from total energy expenditure on board, annual food production and space farming techniques [PDF]
In the first papers of our series on interstellar generation ships we have demonstrated that the numerical code HERITAGE is able to calculate the success rate of multi-generational space missions. Thanks to the social and breeding constraints we examined, a multi-generational crew can safely reach an exoplanet after centuries of deep space travel ...
arxiv
Predicting DNA fragmentation: A non-destructive analogue to chemical assays using machine learning [PDF]
Globally, infertility rates are increasing, with 2.5\% of all births being assisted by in vitro fertilisation (IVF) in 2022. Male infertility is the cause for approximately half of these cases. The quality of sperm DNA has substantial impact on the success of IVF.
arxiv