Results 41 to 50 of about 224,723 (313)

Intraovarian platelet-rich plasma injection significantly improves blastocyst yield and quality in IVF patients

Scientific Reports
This study evaluated the effectiveness of intraovarian platelet-rich plasma (PRP) injection in improving ovarian response and embryo quality in IVF patients with poor embryo quality in previous controlled ovarian hyperstimulation (COH) cycles.
Tzu-Ning Yu, Ming-Jer Chen, Tsung-Hsien Lee, Yi-Chun Chen, En-Hui Cheng, Chun-Chia Huang, Chung-I Chen, Chun-I Lee, Maw-Sheng Lee, Pin-Yao Lin   +9 more
doaj   +1 more source

Prevalence of Chlamydia trachomatis, Ureaplasma spp., Mycoplasma genitalium and Mycoplasma hominis among outpatients in central Greece: absence of tetracycline resistance gene tet(M) over a 4-year period study

New Microbes and New Infections, 2016
A total of 301 men and women attending local urologists and gynaecologists in the state of Thessaly, central Greece, were tested for Chlamydia trachomatis, Ureaplasma spp., Mycoplasma genitalium and Mycoplasma hominis DNA.
A. Ikonomidis, C. Venetis, D. Georgantzis, V. Giaslakiotis, V. Kolovos, K. Efstathiou, M. Moschou, Ε. Κoutsiaris, M. Panopoulou   +8 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Developmental potential of oocytes fertilized by conventional in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) after cryopreservation and mesometrial autotransplantation of rabbit ovarian tissue

Animal, 2008
Objective: To evaluate mesometrial transplantation of frozen-thawed ovarian tissue in rabbit and to choose the optimized fertilization method for oocytes retrieved from grafts by investigating the capability of oocyte fertilization and further ...
C. Lan, D. Xiaohui, F. Qingzhao, X. Anran, H. Chun-yan, Y. Hongling, Y. Xuan   +6 more
doaj   +1 more source

The Pregnancy Outcomes of Day 2 versus Day 3 Embryo Transfer: A Cross-Sectional Study [PDF]

International Journal of Fertility and Sterility, 2007
Background: The objective was to evaluate whether extending the embryo culture period from 2 to 3 days would yield a more optimal selection of viable embryos, thereby increasing the pregnancy rate.Materials and Methods: We have retrospectively analyzed ...
Mahnaz Ashrafi, Kiandokht Kiani, Elahe Mirzaagha, Fatemeh Shabani   +3 more
doaj   +1 more source

Blastocyst Morphology Based on Uniform Time-Point Assessments is Correlated With Mosaic Levels in Embryos

Frontiers in Genetics, 2021
Avoiding aneuploid embryo transfers has been shown to improve pregnancy outcomes in patients with implantation failure and pregnancy loss. This retrospective cohort study aims to analyze the correlation of time-lapse (TL)-based variables and numeric ...
Chien-Hong Chen, Chun-I Lee, Chun-I Lee, Chun-I Lee, Chun-Chia Huang, Hsiu-Hui Chen, Shu-Ting Ho, En-Hui Cheng, Pin‐Yao Lin, Chung-I Chen, Tsung-Hsien Lee, Tsung-Hsien Lee, Tsung-Hsien Lee, Maw-Sheng Lee, Maw-Sheng Lee, Maw-Sheng Lee   +15 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Pregnancy Outcome of Singletons in IVF/ ICSI Cycles: A Cross-Sectional Study [PDF]

International Journal of Fertility and Sterility, 2007
Background: The aim of this study was to compare prenatal outcome of intra cytoplasmic sperm injection (ICSI) pregnancies with pregnancies obtained through in vitro fertilization (IVF).Materials and Methods: Retrospectively 532 pregnancies of ART cycles ...
Mahnaz Ashrafi, Robabeh Khalesi, Tahereh Madani, Kiandokht Kiani, Fatemeh Rastegar, Fatemeh Shabani   +5 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source