Results 21 to 30 of about 213,507 (248)

Successful Outcome Following Hysteroscopic Septoplasty in a Woman with Seven Consecutive Pregnancy Losses

Fertility & Reproduction, 2021
Anomalies of the reproductive tract are common and present in about 3%–5% of the general population and in about 3% of infertile women. In general, they are asymptomatic, but they can also be associated with recurrent abortions or infertility.
Jesmine Banu, Mumtahena Amir, Shakeela Ishrat, Sadia Afrin Munmun, Nighat Sultana   +4 more
doaj   +1 more source

Investigating developmental characteristics of biopsied blastocysts stratified by mitochondrial copy numbers using time-lapse monitoring

Reproductive Biology and Endocrinology
Background For in vitro fertilization (IVF), mitochondrial DNA (mtDNA) levels in the trophectodermal (TE) cells of biopsied blastocysts have been suggested to be associated with the cells’ developmental potential. However, scholars have reached differing
Chun-I Lee, Ching-Ya Su, Hsiu-Hui Chen, Chun-Chia Huang, En-Hui Cheng, Tsung-Hsien Lee, Pin-Yao Lin, Tzu-Ning Yu, Chung-I Chen, Ming-Jer Chen, Maw-Sheng Lee, Chien-Hong Chen   +11 more
doaj   +1 more source

Transvaginal sonography and surgical findings in the diagnosis of endometriosis individuals: A cross-sectional study

International Journal of Reproductive BioMedicine, 2023
Background: Endometriosis is a challenging gynecological disease and a debilitating condition that profoundly affects the individual's quality of life.
Roya Padmehr, Khadijeh Shadjoo, Arash Mohazzab, Atefeh Gorgin, Roxana Karegar, Parvin Jaberipour, Zahra Sehat, Narges Maleki   +7 more
doaj   +1 more source

The Effects of Cabergoline Compared to Dienogest in Women with Symptomatic Endometrioma

Fertility & Reproduction, 2021
Background: New vessel formation or neovascularization has been recognized as a feature of endometriosis. Treatment with cabergoline suppresses cell proliferation and vascular-endothelial-growth-factor-mediated angiogenesis, thereby promoting regression ...
Mehnaz Mustary Shume, Jesmine Banu, Shakeela Ishrat, Serajoom Munira, Muhammad Jasim Uddin, Sabiha Sultana   +5 more
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Extended blastocyst culture improves DNA yield in non-invasive preimplantation genetic testing for aneuploidy but diagnostic specificity remains limited

Scientific Reports
Non-invasive preimplantation genetic testing for aneuploidy (niPGT-A), which analyzes cell-free DNA (cfDNA) from spent culture media (SCM), has emerged as a proposed alternative to trophectoderm (TE) biopsy in in vitro fertilization (IVF).
Ting-Feng Wu, Chun-I Lee, Hui-Hsin Shih, En-Hui Cheng, Chun-Chia Huang, Tsung-Hsien Lee, Maw-Sheng Lee, Pin-Yao Lin   +7 more
doaj   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Associations between the artificial intelligence scoring system and live birth outcomes in preimplantation genetic testing for aneuploidy cycles

Reproductive Biology and Endocrinology
Background Several studies have demonstrated that iDAScore is more accurate in predicting pregnancy outcomes in cycles without preimplantation genetic testing for aneuploidy (PGT-A) compared to KIDScore and the Gardner criteria.
Chun-I Lee, Chun-Chia Huang, Tsung-Hsien Lee, Hsiu-Hui Chen, En-Hui Cheng, Pin-Yao Lin, Tzu-Ning Yu, Chung-I Chen, Chien-Hong Chen, Maw-Sheng Lee   +9 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Intraovarian platelet-rich plasma injection significantly improves blastocyst yield and quality in IVF patients

Scientific Reports
This study evaluated the effectiveness of intraovarian platelet-rich plasma (PRP) injection in improving ovarian response and embryo quality in IVF patients with poor embryo quality in previous controlled ovarian hyperstimulation (COH) cycles.
Tzu-Ning Yu, Ming-Jer Chen, Tsung-Hsien Lee, Yi-Chun Chen, En-Hui Cheng, Chun-Chia Huang, Chung-I Chen, Chun-I Lee, Maw-Sheng Lee, Pin-Yao Lin   +9 more
doaj   +1 more source