Results 41 to 50 of about 418,085 (342)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Intraovarian platelet-rich plasma injection significantly improves blastocyst yield and quality in IVF patients

Scientific Reports
This study evaluated the effectiveness of intraovarian platelet-rich plasma (PRP) injection in improving ovarian response and embryo quality in IVF patients with poor embryo quality in previous controlled ovarian hyperstimulation (COH) cycles.
Tzu-Ning Yu, Ming-Jer Chen, Tsung-Hsien Lee, Yi-Chun Chen, En-Hui Cheng, Chun-Chia Huang, Chung-I Chen, Chun-I Lee, Maw-Sheng Lee, Pin-Yao Lin   +9 more
doaj   +1 more source

Contribution of Bacterial Infection to Male Infertility in Nigerians [PDF]

, 2009
There is disagreement as to the influence of certain microbial infection on male infertility and such agents are ignored. The incidence of these microbial agents in seminal fluid isolates is on the increase.
Emokpae, MA, Sadiq, NM, Uadia, PO
core   +1 more source

Anorexia nervosa and reproduction: connecting brain to gonads [PDF]

, 2020
Anorexia nervosa (AN) is a psychiatric disorder that predominantly affects young women and is characterized by low caloric intake and a major dissatisfaction with one’s body image.
Ciobanu, Corina, Fica, Simona, Poterasu, Mihaela, Rowland, David L.   +3 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Assessment of questionnaires measuring quality of life in infertile couples: A systematic review [PDF]

, 2013
Background: Infertility has potentially inappropriate effects on quality of life in infertile couples. Various general and specific questionnaires have been structured for assessing different aspects of quality of life in infertile men, women, or couples.
Keramat, A., Masoumi, S.Z., Mousavi, S.A., Pooralajal, J., Shobeiri, F.   +4 more
core   +1 more source

Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities [PDF]

, 2015
Background : Observational studies suggest higher pregnancy rates after the hysteroscopic removal of endometrial polyps, submucous fibroids, uterine septum or intrauterine adhesions, which are detectable in 10% to 15% of women seeking treatment for ...
Bosteels, Jan, Broekmans, Frank J, D'Hooghe, Thomas M, Kasius, Jenneke, Mol, Ben Willem J, Weyers, Steven   +5 more
core   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Factors associated with failed treatment : an analysis of 121,744 women embarking on their first IVF cycles [PDF]

, 2013
Peer reviewedPublisher ...
A Strandell, A Templeton, Abha Maheshwari, AM Stolwijk, AP Ferraretti, B Maugey-Laulom, CC Hunault, CH Syrop, DA Lawlor, E Hauzman, G Zou, Guy Brock, Jill Mollison, JK Min, K Ferlitsch, L Sabatini, LA McNutt, LD Ottosen, LF Bancsi, LL van Loendersloot, LL Van Loendersloot, MH van der Gaast, N Johnson, R Hart, S Greenland, Siladitya Bhattacharya, SK Sunkara, SM Ebbesen, SM Nelson, V Sharma, YA Wang   +30 more
core   +3 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source