Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration
Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman +5 more
wiley +1 more source
Environmental determinants of male infertility: emerging threats and technological interventions. [PDF]
Jagadesh P, Sridharan TB.
europepmc +1 more source
A BioLiving Periosteum Evokes Centripetal Regeneration in Challenging Bone Defects
Large bone defects often suffer from insufficient central healing. This study engineers a BioLiving periosteum that mimics the native structure. It sequentially delivers remote chemical cues and contact physical cues in a signaling‐relay manner, effectively recruiting and guiding endogenous cells toward the defect center.
Yang Shi +12 more
wiley +1 more source
Celastrol upregulates adipocyte‐derived exosomal miR‐5099, suppressing the macrophage c‐Met/NF‐κB axis to mitigate pro‐inflammatory M1 polarization and adipose inflammation. These miR‐5099‐enriched exosomes also act as endocrine signals targeting the liver, muscle, and adipocytes to significantly enhance systemic insulin sensitivity.
Ping Tang +9 more
wiley +1 more source
Male infertility as a critical equity case: reframing nursing epistemologies through masculinities and justice-oriented reflexivity. [PDF]
Abdullahzadeh M.
europepmc +1 more source
Routine psychosocial care in infertility and medically assisted reproduction – A guide for fertility staff: Summary [PDF]
ESHRE Psychology and Counselling Guideline Development Group +1 more
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Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak +9 more
wiley +1 more source
Prevalence of chromosomal abnormalities and polymorphisms in 4,672 infertile patients undergoing assisted reproductive techniques in the United Arab Emirates population. [PDF]
Upadhyay D +5 more
europepmc +1 more source
Routine psychosocial care in infertility and medically assisted reproduction - a guide for fertility staff: External Review Report [PDF]
Baor, Liora +13 more
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