Results 81 to 90 of about 279,078 (329)
FEBS Open Bio, EarlyView.Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley +1 more source
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
FEBS Open Bio, EarlyView.This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Menger’s theorem for infinite graphs [PDF]
Inventiones mathematicae, 2008 We prove that Menger's theorem is valid for infinite graphs, in the following strong form: let $A$ and $B$ be two sets of vertices in a possibly infinite digraph. Then there exist a set $\cp$ of disjoint $A$-$B$ paths, and a set $S$ of vertices separating $A$ from $B$, such that $S$ consists of a choice of precisely one vertex from each path in $\cp ...
Aharoni, Ron, Berger, Eli
openaire +3 more sources
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Constructing Infinite One-regular Graphs
European Journal of Combinatorics, 1999 A graph \(X\) is said to be one-regular if the automorphism group of \(X\) acts regularly on the set of arcs of \(X\). The authors consider infinite one-regular graphs. Starting with an infinite family of finite one-regular graphs of valency 4, for each member of this family an infinite one-regular graph is constructed.
Malnič, Aleksander +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Every infinitely edge-connected graph contains the Farey graph or $${T_{\aleph _0}*t}$$ as a minor [PDF]
, 2021 Jan Kurkofka
openalex +1 more source
The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen +5 more
wiley +1 more source
, 2018 We discover new hereditary classes of graphs that are minimal (with respect to set inclusion) of unbounded clique-width. The new examples include split permutation graphs and bichain graphs.
Atminas, A. +3 more
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