Results 51 to 60 of about 4,545,650 (236)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Infinite Product Representation for the Szegö Kernel for an Annulus

open access: yesJournal of Function Spaces, 2022
The Szegö kernel has many applications to problems in conformal mapping and satisfies the Kerzman-Stein integral equation. The Szegö kernel for an annulus can be expressed as a bilateral series and has a unique zero.
Nuraddeen S. Gafai   +2 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Tail probabilities for Infinite series of Regularly Varying Random Sectors [PDF]

open access: yes, 2007
Tail probabilities for Infinite series of Regularly Varying Random ...
Samorodnitsky, G., Hult, H.
core   +4 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

On an inequality suggested by Littlewood

open access: yesJournal of Inequalities and Applications, 2011
We study an inequality suggested by Littlewood, our result refines a result of Bennett. 2000 Mathematics Subject Classification. Primary 26D15.
Gao Peng
doaj  

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

On Indexed Absolute Matrix Summability of an Infinite Series [PDF]

open access: yes, 2018
Some results have been established on absolute index Riesz summability factor of an infinite series. Furthermore, these kind of results can be extended by taking other parameters and an absolute index matrix summability factor of an infinite series or ...
Mishra, Lakshmi N.   +4 more
core   +1 more source

A test for nonlinearity of time series with infinite variance

open access: yes, 1998
A test for nonlinearity of time series with infinite ...
Resnick, S., van den Berg, E.
core   +5 more sources

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