Results 181 to 190 of about 90,432 (374)

Type I interferon signaling is required for activation of the inflammasome during Francisella infection [PDF]

, 2007
Thomas Henry, Anna Brotcke, David S. Weiss, Lucinda J. Thompson, Denise M. Monack   +4 more
openalex   +1 more source

LPS‐Induced Mitochondrial Damage via SLC41A1‐Mediated Magnesium Ion Efflux Leads to the Pyroptosis of Dental Stem Cells

Advanced Science, EarlyView.
Lipopolysaccharide induces upregulation of the magnesium (Mg2+) efflux transporter solute carrier family 41 member 1 in dental stem cells, leading to a decrease in intracellular Mg2+ concentration and promoting the binding of oligomycin sensitivity‐conferring protein and cyclophilinD.
Yuan Liu, Chenyu Song, Liyuan Zhang, Xue Han, Chaoyuan Li, Yanhong Yan, Ludan Xing, Mengting Si, Bo Yang, Lingyuan Cheng, Akimi Muramatsu, Beizhan Jiang   +11 more
wiley   +1 more source

Variations in Innate Immune Cell Subtypes Correlate with Epigenetic Clocks, Inflammaging and Health Outcomes

Advanced Science, EarlyView.
This study uses a high‐resolution DNA methylation reference panel for 19 immune cell‐types, as well as transcriptomic, metabolomic, and large population cohort data to show that age‐related epigenetic heterogeneity within monocytes correlates with inflammaging, biological age, and all‐causemortality, and does so more strongly than existing monocyte ...
Xiaolong Guo, Josephine A. Robertson, Andrea Aparicio, Kirsten Seale, Qingwen Chen, Anne Richmond, Zhaozhen Du, Mahnoor Sulaiman, Shijie C Zheng, Esteban Ballestar, Charlotte AM Cecil, Bastiaan T Heijmans, Steve Horvath, Varun B. Dwaraka, Jessica Lasky‐Su, Ryan Smith, Riccardo E. Marioni, Andrew E Teschendorff   +17 more
wiley   +1 more source

The inflammasome in pathogen recognition and inflammation [PDF]

, 2007
Fayyaz S. Sutterwala, Yasunori Ogura, Richard A. Flavell   +2 more
openalex   +1 more source

Suppressive effects of medicinal plants and their derivatives on inflammasome complex: A systematic review [PDF]

, 2016
Inflammasome activation is mediated by (NOD)-like receptors (NLR) proteins that respond to stimuli. Among NLRs, NACHT-LRR and PYD domains-containing protein 3 (NLRP3) senses the widest array of stimuli.
Asadi-Samani, Majid., Bahmani, Mahmoud., Banitalebi Dehkordi, Mehdi., Mahmoudian Sani, Mohammad Reza., Saeedi-Boroujeni, Ali.   +4 more
core  

Onion‐Mitochondria Inhibit Lipopolysaccharide‐Induced Acute Lung Injury by Shaping Lung Macrophage Mitochondrial Function

Advanced Science, EarlyView.
Proposed model of orally administered onion mitochondria (O‐Mit) uptake by lung macrophages and fuse with macrophage mitochondria (M‐Mit). This fusion reprograms the metabolism of dysfunctional M‐Mit in lipopolysaccharide‐induced murine acute lung injury by modulating dynamin‐related protein 1 (DRP1) phosphorylation and cardiolipin peroxidation ...
Qingbo Xu, Yun Teng, Yinan Huang, Jingyao Mu, Lucy Teng, Hongjia Qian, Qiming Huang, Minmin Liu, Yi Zou, Lifeng Zhang, Michael L Merchant, Xiang Zhang, Jun Yan, Huang‐Ge Zhang   +13 more
wiley   +1 more source

NALP1 and the inflammasomes: challenging our perception of vitiligo and vitiligo‐related autoimmune disorders [PDF]

, 2007
Alain Taı̈eb
openalex   +1 more source

Vinburnine Sensitizes Radiotherapy Efficacy in Nasopharyngeal Carcinoma by Triggering Pyroptosis and Immune Responses via Activation of EDAR‐NFκB Pathway

Advanced Science, EarlyView.
This study demonstrates that vinburnine, an approved cerebrovascular drug, synergizes with radiotherapy in nasopharyngeal carcinoma (NPC) by modulating EDAR‐NFκB signaling through directly binding to EDAR, leading to triggering apoptosis/pyroptosis, and amplifying CCL5/CX3CL1‐driven T‐cell cytotoxicity.
Jing Chen, Nian Liu, Qian Tao, Jie Wu, Jinyu Huang, Can Lu, Qiuqiu Li, Liangfang Shen, Xiang Chen, Cong Peng   +9 more
wiley   +1 more source

Elucidating the molecular landscape of tendinitis: the role of inflammasome-related genes and immune interactions

Frontiers in Immunology
Tendinitis, characterized by the inflammation of tendons, poses significant challenges in both diagnosis and treatment due to its multifaceted etiology and complex pathophysiology.
Hongwei Xu, Xiaolang Lu, Yang Yu, Yifei Zhou, Tengfei Qi, Yijing Zheng   +5 more
doaj   +1 more source

Caspase-1 inflammasomes: choosing between death and taxis [PDF]

, 2007
Maya Saleh, Douglas R. Green
openalex   +1 more source