Results 11 to 20 of about 3,471,024 (333)
Current Immunology Reviews, 2008 The past few years of research on leptin have provided important information on the link between metabolism and immune homeostasis. Adipocytes influence not only the endocrine system but also the immune response through several cytokine-like mediators known as adipokines, which include leptin.
Iikuni N +4 more
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Sphingolipids in Inflammation [PDF]
Mediators of Inflammation, 2018 The etiology of many diseases results from the dysregulation of inflammation. Understanding the molecular mechanisms controlling the inflammatory response is essential to formulate therapeutic strategies for the treatment of inflammatory conditions. In fact, substantial research has unveiled important aspects of the inflammatory machinery, both at the ...
Elisabetta Albi +2 more
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Вопросы современной педиатрии, 2006 In the article the characteristic of ethiology and key parts of pathogenesis of inflammation is given; modern data on the role of adhesive molecules, active forms of oxygen, lipoperoxidation processes, cytokines and other mediators in the development of acute and chronic inflammation are analyzed; the principles of its treatment are substantiated.Key ...
Elgazzar, Abdelhamid H. +1 more
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Acta Neuropathologica Communications, 2021 Alzheimer’s disease (AD) is a chronic neurodegenerative disease characterized by the accumulation of amyloid β (Aβ) and neurofibrillary tangles. The last decade, it became increasingly clear that neuroinflammation plays a key role in both the initiation ...
Junhua Xie +10 more
doaj +1 more source
EJNMMI Research, 2021 Inflammatory musculoskeletal diseases represent a group of chronic and disabling conditions that evolve from a complex interplay between genetic and environmental factors that cause perturbations in innate and adaptive immune responses. Understanding the
Erik H. J. G. Aarntzen +10 more
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Histopathology of the gut in rheumatic diseases [PDF]
, 2018 The gastrointestinal tract regulates the trafficking of macromolecules between the environment and the host through an epithelial barrier mechanism and is an important part of the immune system controlling the equilibrium between tolerance and immunity ...
Ciccia F. +4 more
core +1 more source
Mediators of Inflammation, 2015 Cachexia is a complex wasting syndrome associated with a marked detrimental effect upon life quality and survival in patients with cancer, chronic obstructive pulmonary disease (COPD), chronic heart failure, AIDS, and chronic kidney disease, among other conditions. Its prevalence is of around 5 to 15% in cardiac patients at end stage, rising up to 30%,
Seelaender M. +5 more
openaire +6 more sources
Serum hyaluronate as a non-invasive marker of hepatic fibrosis and inflammation in HBeAg-negative chronic hepatitis B [PDF]
, 2005 Background: HBV infection is a serious global heath problem. It is crucial to monitor this disease more closely with a non-invasive marker in clinical trials.
Derakhshan, M.H. +9 more
core +4 more sources
Contemporary views on inflammatory pain mechanisms: TRPing over innate and microglial pathways. [PDF]
, 2016 Tissue injury, whether by trauma, surgical intervention, metabolic dysfunction, ischemia, or infection, evokes a complex cellular response (inflammation) that is associated with painful hyperalgesic states.
Guan, Zhonghui +2 more
core +2 more sources