Results 11 to 20 of about 2,988,531 (194)
EJNMMI Research, 2021 Inflammatory musculoskeletal diseases represent a group of chronic and disabling conditions that evolve from a complex interplay between genetic and environmental factors that cause perturbations in innate and adaptive immune responses. Understanding the
Erik H. J. G. Aarntzen +10 more
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Acta Neuropathologica Communications, 2021 Alzheimer’s disease (AD) is a chronic neurodegenerative disease characterized by the accumulation of amyloid β (Aβ) and neurofibrillary tangles. The last decade, it became increasingly clear that neuroinflammation plays a key role in both the initiation ...
Junhua Xie +10 more
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Inflammatory responses and inflammation-associated diseases in organs
OncoTarget, 2015 Inflammation is a biological response of the immune system that can be triggered by a variety of factors, including pathogens, damaged cells and toxic compounds. These factors may induce acute and/or chronic inflammatory responses in the heart, pancreas,
Linlin Chen +8 more
semanticscholar +1 more source
Viral dosing of influenza A infection reveals involvement of RIPK3 and FADD, but not MLKL
Cell Death and Disease, 2021 RIPK3 was reported to play an important role in the protection against influenza A virus (IAV) in vivo. Here we show that the requirement of RIPK3 for protection against IAV infection in vivo is only apparent within a limited dose range of IAV challenge.
Teodora Oltean +7 more
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Biomedicines, 2022 Prostate cancer (PCa) is one of the most common cancer types in men and represents an increasing global problem due to the modern Western lifestyle. The signalling adapter protein CARD14 is specifically expressed in epithelial cells, where it has been ...
Domien Vanneste +9 more
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Role of C-Reactive Protein at Sites of Inflammation and Infection
Frontiers in Immunology, 2018 C-reactive protein (CRP) is an acute inflammatory protein that increases up to 1,000-fold at sites of infection or inflammation. CRP is produced as a homopentameric protein, termed native CRP (nCRP), which can irreversibly dissociate at sites of ...
Nicola R. Sproston, J. Ashworth
semanticscholar +1 more source
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
Journal of Experimental Medicine, 2005 Interleukin (IL)-23 is a heterodimeric cytokine composed of a unique p19 subunit, and a common p40 subunit shared with IL-12. IL-12 is important for the development of T helper (Th)1 cells that are essential for host defense and tumor suppression.
C. Langrish +8 more
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Therapeutic Efficacy of Flavonoids in Allergies: A Systematic Review of Randomized Controlled Trials
Journal of Immunology Research, 2022 Objective. To assess the clinical efficacy of flavonoid supplements on allergic diseases. Design. Systematic review. Data Sources. MEDLINE/PubMed, Scopus, Web of Science, and Embase databases were searched from inception to September 2021.
Poliana Guiomar de Almeida Brasiel +4 more
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Glucocorticoid‐induced microRNA‐511 protects against TNF by down‐regulating TNFR1
EMBO Molecular Medicine, 2015 TNF is a central actor during inflammation and a well‐recognized drug target for inflammatory diseases. We found that the mouse strain SPRET/Ei, known for extreme and dominant resistance against TNF‐induced shock, displays weak expression of TNF receptor
Leen Puimège +11 more
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Neutrophil-Derived IL-6 Potentially Drives Ferroptosis Resistance in B Cells in Lupus Kidney
Mediators of Inflammation, 2023 Ferroptosis resistance is vital for B cell development, especially in inflammatory diseases, yet the underlying mechanism is still unclear. In this study, based on the scRNA-seq technique and flow cytometry, we discovered a proportion of neutrophils ...
Zechen Wang +9 more
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