Results 201 to 210 of about 4,758,008 (341)

Serum miRNA Signatures in Cancer Cachexia Depend on Systemic Inflammation. [PDF]

Curr Oncol
Karlsen TLS, Mjelle R, Vagnildhaug OM, Balstad TR, Kristensen AK, Slagsvold JE, Westwik GS, Elvebakken H, Hofsli E, Hatlevoll I, Solheim TS.   +10 more
europepmc   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

RETRACTION: Inhibitory Effect of Matrine on Blood-Brain Barrier Disruption for the Treatment of Experimental Autoimmune Encephalomyelitis

Mediators of Inflammation
Mediators of Inflammation
doaj   +1 more source

From Senescent Cells to Systemic Inflammation: The Role of Inflammaging in Age-Related Diseases and Kidney Dysfunction. [PDF]

Cells
Luca F, Camporeale V, Leccese G, Cuttano R, Troise D, Infante B, Stallone G, Netti GS, Ranieri E.   +8 more
europepmc   +1 more source

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance.

Journal of Clinical Investigation, 2003
Haiyan Xu, Glenn Barnes, Qing Yang, G. Tan, Daseng Yang, C. Chou, Jason Sole, A. Nichols, J. Ross, L. Tartaglia, Hong Chen   +10 more
semanticscholar   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Exploring the impact of pan-immune-inflammation-value and other traditional inflammation-based markers on coronary collateral circulation in patients with chronic total occlusion. [PDF]

BMC Cardiovasc Disord
Toprak K, Karataş M.
europepmc   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Acute Inflammation Alters Brain Energy Metabolism in Mice and Humans: Role in Suppressed Spontaneous Activity, Impaired Cognition, and Delirium [PDF]

, 2020
John Kealy, Carol Murray, Éadaoin W. Griffin, Ana Belén López-Rodríguez, Dáire Healy, Lucas Silva Tortorelli, John Lowry, Leiv Otto Watne, Colm Cunningham   +8 more
openalex   +1 more source

Systemic inflammation indices measured shortly before delivery are not associated with preterm birth in pregnant women with endometriosis. [PDF]

BMC Pregnancy Childbirth
Chen Y, Chen M, Li J, Hu L, Zhao M, Gu Y, Chen Q.   +6 more
europepmc   +1 more source