Results 31 to 40 of about 3,471,024 (333)
Viral dosing of influenza A infection reveals involvement of RIPK3 and FADD, but not MLKL
Cell Death and Disease, 2021 RIPK3 was reported to play an important role in the protection against influenza A virus (IAV) in vivo. Here we show that the requirement of RIPK3 for protection against IAV infection in vivo is only apparent within a limited dose range of IAV challenge.
Teodora Oltean +7 more
doaj +1 more source
Biomedicines, 2022 Prostate cancer (PCa) is one of the most common cancer types in men and represents an increasing global problem due to the modern Western lifestyle. The signalling adapter protein CARD14 is specifically expressed in epithelial cells, where it has been ...
Domien Vanneste +9 more
doaj +1 more source
Roles of tumor suppressors in regulating tumor-associated inflammation. [PDF]
, 2014 Loss or silencing of tumor suppressors (TSs) promotes neoplastic transformation and malignant progression. To date, most work on TS has focused on their cell autonomous effects.
Karin, M, Yang, L
core +1 more source
Effects of lipopolysaccharide-induced inflammation on expression of growth-associated genes by corticospinal neurons [PDF]
, 2006 Background: Inflammation around cell bodies of primary sensory neurons and retinal ganglion cells enhances expression of neuronal growth-associated genes and stimulates axonal regeneration.
Anderson, PN +5 more
core +2 more sources
An Inflammation-Centric View of Neurological Disease: Beyond the Neuron [PDF]
, 2018 Inflammation is a complex biological response fundamental to how the body deals with injury and infection to eliminate the initial cause of cell injury and effect repair.
Facci, Laura +3 more
core +2 more sources
Glucocorticoid‐induced microRNA‐511 protects against TNF by down‐regulating TNFR1
EMBO Molecular Medicine, 2015 TNF is a central actor during inflammation and a well‐recognized drug target for inflammatory diseases. We found that the mouse strain SPRET/Ei, known for extreme and dominant resistance against TNF‐induced shock, displays weak expression of TNF receptor
Leen Puimège +11 more
doaj +1 more source
Neutrophil-Derived IL-6 Potentially Drives Ferroptosis Resistance in B Cells in Lupus Kidney
Mediators of Inflammation, 2023 Ferroptosis resistance is vital for B cell development, especially in inflammatory diseases, yet the underlying mechanism is still unclear. In this study, based on the scRNA-seq technique and flow cytometry, we discovered a proportion of neutrophils ...
Zechen Wang +9 more
doaj +1 more source
Nutrition & Metabolism, 2020 Background Irritable Bowel Syndrome (IBS) is a widespread disease with variable symptoms that have an important impact on the quality of life. Despite the prevalence of IBS, its etiology and pathophysiology are still to be fully understood, but immune ...
Mattia Cappelletti +6 more
doaj +1 more source
Journal of Immunology Research, 2021 We performed a panoramic analysis on both human nonalcoholic steatohepatitis (NASH) microarray data and microarray/RNA-seq data from various mouse models of nonalcoholic fatty liver disease NASH/NAFLD with total 4249 genes examined and made the following
Charles I. V. Drummer +13 more
doaj +1 more source
Autophagy and inflammation [PDF]
Clinical and Translational Medicine, 2017 AbstractAutophagy is a homeostatic mechanism involved in the disposal of damaged organelles, denatured proteins as well as invaded pathogens through a lysosomal degradation pathway. Recently, increasing evidences have demonstrated its role in both innate and adaptive immunity, and thereby influence the pathogenesis of inflammatory diseases.
Xiangdong Wang +2 more
openaire +4 more sources