Volume of hyperintense inflammation (VHI): a deep learning-enabled quantitative imaging biomarker of inflammation load in spondyloarthritis [PDF]
arXiv, 2021 Short inversion time inversion recovery (STIR) MRI is widely used in clinical practice to identify and quantify inflammation in axial spondyloarthritis. However, assessment of STIR images is limited by the need for qualitative evaluation, which depends on observer experience and expertise, creating substantial variability in inflammation assessments ...
arxiv
A qualitative analysis of a A$β$-monomer model with inflammation processes for Alzheimer's disease [PDF]
arXiv, 2022 We introduce and study a new model for the progression of Alzheimer's disease incorporating the interactions of A$\beta$-monomers, oligomers, microglial cells and interleukins with neurons through different mechanisms such as protein polymerization, inflammation processes and neural stress reactions.
arxiv
The vagus nerve regulates immunometabolic homeostasis in the ovine fetus near term: impact on terminal ileum [PDF]
arXiv, 2022 The contribution of the vagus nerve to inflammation and glucosensing in the fetus is not understood. We hypothesized that vagotomy (Vx) will trigger a rise in systemic glucose levels and this will be enhanced during systemic and organ-specific inflammation. Efferent vagus nerve stimulation (VNS) should reverse this phenotype.
arxiv
Association Between Cytokines and Liver Histology in Children with Nonalcoholic Fatty Liver Disease. [PDF]
, 2017 BackgroundReliable non-invasive markers to characterize inflammation, hepatocellular ballooning, and fibrosis in nonalcoholic fatty liver disease (NAFLD) are lacking.
Ann Scheimann +14 more
core +1 more source
Pathologic evaluation of tumor-associated macrophage density and vessel inflammation in invasive breast carcinomas [PDF]
, 2017 Tumor-associated macrophages (TAMs) are major constituents of the tumor microenvironment in solid tumors and have been implicated as mediators of tumor progression, invasion and metastasis.
Adhikari, Smita +7 more
core +2 more sources
Peripheral inflammation is associated with remote global gene expression changes in the brain [PDF]
, 2014 Background: Although the central nervous system (CNS) was once considered an immunologically privileged site, in recent years it has become increasingly evident that cross talk between the immune system and the CNS does occur. As a result, patients with
Cavanagh, Jonathan +3 more
core +2 more sources
Journal of Clinical Investigation, 2003 Insulin resistance arises from the inability of insulin to act normally in regulating nutrient metabolism in peripheral tissues. Increasing evidence from human population studies and animal research has established correlative as well as causative links ...
Haiyan Xu +10 more
semanticscholar +1 more source
Serum hyaluronate as a non-invasive marker of hepatic fibrosis and inflammation in HBeAg-negative chronic hepatitis B [PDF]
, 2005 Background: HBV infection is a serious global heath problem. It is crucial to monitor this disease more closely with a non-invasive marker in clinical trials.
Derakhshan, M.H. +9 more
core +4 more sources
Inflammation and immune dysfunction in Parkinson disease
Nature reviews. Immunology, 2022 Parkinson disease (PD) is a progressive neurodegenerative disease that affects peripheral organs as well as the central nervous system and involves a fundamental role of neuroinflammation in its pathophysiology. Neurohistological and neuroimaging studies
M. Tansey +5 more
semanticscholar +1 more source
Automated Detection of Persistent Inflammatory Biomarkers in Post-COVID-19 Patients Using Machine Learning Techniques [PDF]
arXiv, 2023 The COVID-19 pandemic has left a lasting impact on individuals, with many experiencing persistent symptoms, including inflammation, in the post-acute phase of the disease. Detecting and monitoring these inflammatory biomarkers is critical for timely intervention and improved patient outcomes.
arxiv