CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis [PDF]
Macrophages, which are abundant in the tumour microenvironment, enhance malignancy. At metastatic sites, a distinct population of metastasis-associated macrophages promotes the extravasation, seeding and persistent growth of tumour cells.
Pollard, Jeffrey W +17 more
core +1 more source
Smoking in inflammatory bowel diseases: Good, bad or ugly? [PDF]
Smoking is an important environmental factor in inflammatory bowel disease (IBD), having different effects in ulcerative colitis (UC) and Crohn’s disease (CD).
Peter Laszlo Lakatos +5 more
core +1 more source
Diagnosis, treatment and immunopathogenesis of the HIV-associated tuberculosis immune reconstitution inflammatory syndrome [PDF]
The paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) is a frequent complication of antiretroviral therapy (ART) among patients who start ART while on treatment for tuberculosis (TB).
Meintjes, Graeme
core +1 more source
Background Calprotectin is a stable neutrophil protein, which can be measured in faecal samples. The faecal level of calprotectin increases during disease activity in ulcerative colitis (UC).
Takahiro Shimoyama +3 more
doaj +1 more source
The Use of Oral Herbal Medicine (Hange-Shashin-To) in Patients with Pouchitis: A Pilot Study
Objectives: Hange-Shashin-To (HST), which is a combination of seven herbs, has previously been used in the treatment of inflammatory or ulcerative gut disease.
Hiroki Matsuoka +9 more
doaj +1 more source
Immunological characterization of the HIV-tuberculosis associated immune reconstitution inflammatory syndrome [PDF]
While the integration of anti-TB and cART therapies is associated with substantial clinical improvement in the majority of patients, HIV-Tuberculosis associated Immune Reconstitution Inflammatory Syndrome (TB-IRIS) has been shown to occur in a ...
Tadokera, Rabecca
core +1 more source
Rectal-sparing type of ulcerative colitis predicts lack of response to pharmacotherapies
Background Ulcerative colitis (UC) is known as an immune disorder of the colon that generally involves the rectum, but an atypical distribution of inflamed mucosa has previously been noted in certain subtypes of UC, such as the rectal-sparing type (RST).
Yuki Horio +7 more
doaj +1 more source
Traditional concepts of the pathogenesis of acute coronary syndromes have changed over the last few years. In particular it has been demonstrated that high-risk lesions are not necessarily angiographically severe. Rather, unstable high risk lesions are the ones composed of large lipid cores and thin fibrous caps.
A, Farzaneh-Far, J, Rudd, P L, Weissberg
openaire +2 more sources
Inflammatory markers and incident frailty in men and women:the English Longitudinal Study of Ageing [PDF]
Cross-sectional studies show that higher blood concentrations of inflammatory markers tend to be more common in frail older people, but longitudinal evidence that these inflammatory markers are risk factors for frailty is sparse and inconsistent.
Gale, Catharine R +7 more
core +1 more source
“Inflammatory or non-inflammatory pain in inflammatory arthritis – How to differentiate it?”
Pain is a significant issue in rheumatoid arthritis (RA) and psoriatic arthritis (PSA) and can have a negative impact on patients' quality of life. Despite optimal control of inflammatory disease, residual chronic pain remains a major unmet medical need in RA.
Sarzi-Puttini, Piercarlo +9 more
openaire +2 more sources

