Nrf2 deficiency influences susceptibility to steroid resistance via HDAC2 reduction [PDF]
, 2010 Abnormal lung inflammation and oxidant burden are associated with a significant reduction in histone deacetylase 2 (HDAC2) abundance and steroid resistance.
Adenuga +33 more
core +1 more source
Journal of the Anus, Rectum and Colon, 2020 Objectives: Restorative proctocolectomy and ileal pouch anal anastomosis (IPAA), with diverting ileostomy, are established ulcerative colitis (UC) treatments.
Ryuichi Kuwahara +7 more
doaj +1 more source
Novel antioxidant and anti-inflammatory peptides from the Siamese crocodile (Crocodylus siamensis) hemoglobin hydrolysate [PDF]
, 2017 Novel antioxidant and anti-inflammatory peptides were isolated from hydrolysates of Siamese crocodile (Crocodylus siamensis) hemoglobin. C. siamensis hemoglobin hydrolysates (CHHs) were obtained by pepsin digestion at different incubation times (2, 4, 6,
Jangpromma, Nisachon +7 more
core +1 more source
Understanding the role of P2X7 in affective disorders—are glial cells the major players? [PDF]
, 2015 Pathophysiology associated with several psychiatric disorders has been linked to inflammatory biomarkers. This has generated a theory of major depressive disorders as an inflammatory disease.
Jenkins, Trisha A. +2 more
core +2 more sources
Identifying the Hub Genes of Glioma Peritumoral Brain Edema Using Bioinformatical Methods
Brain Sciences, 2022 Glioma peritumoral brain edema (GPTBE) is a frequent complication in patients with glioma. The severity of peritumoral edema endangers patients’ life and prognosis.
Yuxi Wu +3 more
doaj +1 more source
Ischemic Stroke and Acute Coronary Syndrome (ACS) in COVID-19 patients: Mechanisms and Role of Coagulopathy [PDF]
Liaquat National Journal of Primary Care, 2023 COVID-19 has a devastating impact on patients not only due to the severity of pulmonary disease but also the multitude of other manifestations.
Syed Mujtaba Azhar Bokhari +1 more
doaj +1 more source
Signal transduction and activator of transcription-3 (STAT3) in patients with colorectal cancer: associations with the phenotypic features of the tumour and host [PDF]
, 2017 Purpose: In patients with colorectal cancer (CRC), a high-density local inflammatory infiltrate response is associated with improved survival, whereas elevated systemic inflammatory responses are associated with poor survival.
Clark, Jennifer +7 more
core +1 more source
Dimethyl Fumarate Alleviates Dextran Sulfate Sodium-Induced Colitis, through the Activation of Nrf2-Mediated Antioxidant and Anti-inflammatory Pathways. [PDF]
, 2020 Oxidative stress and chronic inflammation play critical roles in the pathogenesis of ulcerative colitis (UC) and inflammatory bowel diseases (IBD). A previous study has demonstrated that dimethyl fumarate (DMF) protects mice from dextran sulfate sodium ...
Farzaneh, Ted +8 more
core +2 more sources
The Use of Oral Herbal Medicine (Hange-Shashin-To) in Patients with Pouchitis: A Pilot Study
Journal of the Anus, Rectum and Colon, 2018 Objectives: Hange-Shashin-To (HST), which is a combination of seven herbs, has previously been used in the treatment of inflammatory or ulcerative gut disease.
Hiroki Matsuoka +9 more
doaj +1 more source
Relationship between tumour PTEN/Akt/COX-2 expression, inflammatory response and survival in patients with colorectal cancer [PDF]
, 2016 In patients with colorectal cancer (CRC), local and systemic inflammatory responses have been extensively reported to associate with cancer survival. However, the specific signalling pathways responsible for inflammatory responses are not clear. The PTEN/
Bennett, Lindsay +7 more
core +3 more sources