Results 41 to 50 of about 4,677,756 (310)

CCR2+ Macrophages Promote Orthodontic Tooth Movement and Alveolar Bone Remodeling

Frontiers in Immunology, 2022
During mechanical force-induced alveolar bone remodeling, macrophage-mediated local inflammation plays a critical role. Yet, the detailed heterogeneity of macrophages is still unknown.
Hao Xu, Hao Xu, Hao Xu, Shuting Zhang, Shuting Zhang, Shuting Zhang, Adwait Amod Sathe, Zhichun Jin, Zhichun Jin, Zhichun Jin, Jiani Guan, Jiani Guan, Jiani Guan, Wen Sun, Chao Xing, Chao Xing, Chao Xing, Hanwen Zhang, Hanwen Zhang, Bin Yan, Bin Yan, Bin Yan   +21 more
doaj   +1 more source

Management of Anal Fistula with Crohn's Disease

Journal of the Anus, Rectum and Colon
Crohn's disease (CD) causes gastrointestinal symptoms (i.e., diarrhea and abdominal pain), systemic symptoms (i.e., fatigue, anemia, weight loss, and fever), and perianal fistulas that produce anal pain. Because of the frequent occurrence of diarrhea and
Shota Takano, Yasushi Nakamura, Kohei Tamaoka, Takafumi Yoshimoto, Yasue Irei, Yoriyuki Tsuji   +5 more
doaj   +1 more source

Genome engineering of stem cells for autonomously regulated, closed-loop delivery of biologic drugs [PDF]

, 2017
Chronic inflammatory diseases such as arthritis are characterized by dysregulated responses to pro-inflammatory cytokines such as interleukin-1 (IL-1) and tumor necrosis factor α (TNF-α).
Brunger, Jonathan M, Gersbach, Charles A, Guilak, Farshid, Willard, Vincent P, Zutshi, Ananya   +4 more
core   +3 more sources

Design of an anti-inflammatory diet (ITIS diet) for patients with rheumatoid arthritis. [PDF]

, 2020
Background:Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects synovial joints, leading to inflammation, joint destruction, loss of function, and disability.
Agustín-Perez, Meritxall, Bustamante, Marta F, Cedola, Francesca, Coras, Roxana, Golshan, Shahrokh, Guma, Monica, Narasimhan, Rekha   +6 more
core   +2 more sources

Immunomodulatory effects of 17-O-acetylacuminolide in RAW264.7 cells and HUVECs : involvement of MAPK and NF-κB pathways [PDF]

, 2014
The terpenoid 17-O-acetylacuminolide (AA) was shown to inhibit the production of several inflammatory mediators. However, the mechanisms by which this compound elicited its anti-inflammatory activity remain to be elucidated.
Achoui, Mouna, Haegeman, Guy, Heyninck, Karen, Looi, Chung Yeng, Mustafa, Ali Mohd, Mustafa, Mohd Rais   +5 more
core   +1 more source

Extracellular signal-regulated kinases mediate the enhancing effects of inflammatory mediators on resurgent currents in dorsal root ganglion neurons [PDF]

, 2019
Previously we reported that a group of inflammatory mediators significantly enhanced resurgent currents in dorsal root ganglion neurons. To understand the underlying intracellular signaling mechanism, we investigated the effects of inhibition of ...
Cummins, Theodore R., Knopp, Kelly L., Krajewski, Jeffrey L., McDermott, Jeff S., Nisenbaum, Eric S., Tan, Zhi-Yong, Wu, Bin   +6 more
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Periappendicular Inflammatory Masses

Turkish Journal of Colorectal Disease, 2020
Aim:Periappendicular inflammatory mass (PIM) defined as a mass located at the right lower quadrant of the abdomen due to inflammation, and can not clearly distinguish from borders of appendix.
Dursun Özgür Karakaş, Metin Yeşiltaş, Berk Gökçek, Seracettin Eğin, Semih Hot   +4 more
doaj   +1 more source

Urinary proteomics can define distinct diagnostic inflammatory arthritis subgroups [PDF]

, 2017
Current diagnostic tests applied to inflammatory arthritis lack the necessary specificity to appropriately categorise patients. There is a need for novel approaches to classify patients with these conditions.
Gaya, Daniel, Hampson, Rosie, Latosinska, Agnieszka, McInnes, Iain, Mischak, Harald, Mullen, William, Paterson, Caron, Porter, Duncan, Schanstra, Joost, Siebert, Stefan   +9 more
core   +2 more sources

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source