Results 71 to 80 of about 6,114,519 (189)

Asthma: where is it going?

Brazilian Journal of Medical and Biological Research, 2008
Asthma is characterized by reversible airway obstruction, airway hyperresponsiveness, and airway inflammation. Although our understanding of its pathophysiological mechanisms continues to evolve, the relative contributions of airway hyperresponsiveness ...
D.S. Faffe
doaj  

Therapeutic potential of elafin in airway inflammatory disease

European Journal of Inflammation
Elafin, which is derived from trappin-2 or pre-elafin by proteolysis, is an endogenous serine protease inhibitor with a low molecular weight. Its inhibitory activity is dependent on anchoring to the extracellular matrix by forming covalent bonds with its
Mingxin He, Yalou Yang, Yanyan Li, Xiangdong Zhou, Li Xu, Ziwei Zhang, Hua Zhang, Qi Li   +7 more
doaj   +1 more source

Investigation of the Anti-Inflammatory Effect of Famotidine in Rats by Evaluation of IL-4, IL-6, TNF-α, and IL-10: Airway Model

Medical Journal of Babylon
Background: Lung inflammatory diseases (such as asthma and chronic obstructive pulmonary disease [COPD])) are widespread inflammatory airway illnesses that are characterized by cough, wheezing, chest tightness, and dyspnea, all of which are symptoms of ...
Wasan Ali Hasan, Manal Abdulkhaliq Ibrahim   +1 more
doaj   +1 more source

Bronchoalveolar lavage fluid lymphocytosis in 104 dogs (2006‐2016)

Journal of Veterinary Internal Medicine, 2019
Background Bronchoalveolar lavage (BAL) fluid cytology and culture are used to characterize respiratory diseases in dogs. Little is known about disorders associated with increased numbers of lymphocytes in BAL fluid.
Lynelle R. Johnson, William Vernau
doaj   +1 more source

FGF2, an Immunomodulatory Factor in Asthma and Chronic Obstructive Pulmonary Disease (COPD)

Frontiers in Cell and Developmental Biology, 2020
The fibroblast growth factor 2 (FGF2) is a potent mitogenic factor belonging to the FGF family. It plays a role in airway remodeling associated with chronic inflammatory airway diseases, including asthma and chronic obstructive pulmonary disease (COPD ...
Yuanyang Tan, Yongkang Qiao, Zhuanggui Chen, Jing Liu, Yanrong Guo, Thai Tran, Kai Sen Tan, De-Yun Wang, Yan Yan, Yan Yan   +9 more
doaj   +1 more source

Airway wall thickening and emphysema show independent familial aggregation in chronic obstructive pulmonary disease.

, 2008
RATIONALE: It is unclear whether airway wall thickening and emphysema make independent contributions to airflow limitation in chronic obstructive pulmonary disease (COPD) and whether these phenotypes cluster within families.
Silverman, E.K., Screaton, N.J., Anderson, W.H., Coxson, H.O., Muller, N.L., Hiorns, M.P., Vestbo, J., Nasute Fauerbach, P.V., Camp, P.G., Patel, B.D., Calverley, P.M., Wouters, E.F., Lomas, D.A., Rennard, S.I., Agusti, A.G., Donner, C.F., Pillai, S.G., Make, B.J., Nakano, Y., Campbell, E.J.   +19 more
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Smoking in inflammatory bowel diseases: Good, bad or ugly? [PDF]

, 2007
Smoking is an important environmental factor in inflammatory bowel disease (IBD), having different effects in ulcerative colitis (UC) and Crohn’s disease (CD).
Peter Laszlo Lakatos, Lakatos, Péter László, Tamas Szamosi, Szamosi, Tamás, Laszlo Lakatos, Lakatos, László   +5 more
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Neutrophil extracellular traps are associated with airways inflammation and increased severity of lung disease in cystic fibrosis

ERJ Open Research
Background Cystic fibrosis (CF) is characterised by inflammatory lung disease and large numbers of airways neutrophils. In health, neutrophils undergo apoptosis and removal from the airway.
Sheonagh M. Law, Gareth Hardisty, Jonathan L. Gillan, Nicola J. Robinson, Donald J. Davidson, Moira K.B. Whyte, Ian Dransfield, Robert D. Gray   +7 more
doaj   +1 more source

Acute and Chronic Effects of Smoking on Inflammation Markers in Exhaled Breath Condensate in Current Smokers [PDF]

, 2010
Background: Long-term cigarette smoking is associated with pulmonary inflammation, but the acute effects of smoking have been less well studied. Analysis of the exhaled breath condensate (EBC) can provide noninvasive markers that might be indicative of ...
Römmelt, Horst, Koczulla, A. Rembert, Herr, Christian, Noeske, Sarah, Vogelmeier, Claus, Bals, Robert, Jörres, Rudolf A.   +6 more
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Effects of soaked hay on lung function and airway inflammation in horses with severe asthma

Journal of Veterinary Internal Medicine
Background Reducing inhaled dust particles improves lung function in horses with severe asthma. Soaked hay is commonly used by owners, but its efficacy in improving lung function and inflammation has not been documented. Objectives To measure the effects
Roxane Westerfeld, Flavie Payette, Valérie Dubuc, Estelle Manguin, Khristine Picotte, Guy Beauchamp, Christian Bédard, Mathilde Leclere   +7 more
doaj   +1 more source