Results 61 to 70 of about 158,758 (202)

IL-18 induces airway hyperresponsiveness and pulmonary inflammation via CD4+ T cell and IL-13. [PDF]

PLoS ONE, 2013
IL-18 plays a key role in the pathogenesis of pulmonary inflammatory diseases including pulmonary infection, pulmonary fibrosis, lung injury and chronic obstructive pulmonary disease (COPD).
Masanori Sawada, Tomotaka Kawayama, Haruki Imaoka, Yuki Sakazaki, Hanako Oda, Shin-ichi Takenaka, Yoichiro Kaku, Koichi Azuma, Morihiro Tajiri, Nobutaka Edakuni, Masaki Okamoto, Seiya Kato, Tomoaki Hoshino   +12 more
doaj   +1 more source

Human Cellular Models for the Investigation of Lung Inflammation and Mucus Production in Cystic Fibrosis

Analytical Cellular Pathology, 2018
Chronic inflammation, oxidative stress, mucus plugging, airway remodeling, and respiratory infections are the hallmarks of the cystic fibrosis (CF) lung disease.
Stefano Castellani, Sante Di Gioia, Lorena di Toma, Massimo Conese   +3 more
doaj   +1 more source

Respiratory Viral Infections in Exacerbation of Chronic Airway Inflammatory Diseases: Novel Mechanisms and Insights From the Upper Airway Epithelium

Frontiers in Cell and Developmental Biology, 2020
Respiratory virus infection is one of the major sources of exacerbation of chronic airway inflammatory diseases. These exacerbations are associated with high morbidity and even mortality worldwide. The current understanding on viral-induced exacerbations
Kai Sen Tan, Rachel Liyu Lim, Jing Liu, Hsiao Hui Ong, Vivian Jiayi Tan, Hui Fang Lim, Hui Fang Lim, Kian Fan Chung, Ian M. Adcock, Vincent T. Chow, De Yun Wang   +10 more
doaj   +1 more source

Interleukin-6 and airflow limitation in chemical warfare patients with chronic obstructive pulmonary disease [PDF]

Objectives: Chronic obstructive pulmonary disease (COPD) is one of the main late complications of sulfur mustard poisoning. The aim of this study was to evaluate serum levels of interleukin (IL)-6 in war veterans with pulmonary complications of sulfur ...
خواجه دلوئی, محمد, Shahrzad Lari, توحیدی, محمد, آیت اللهی, حسین, محمدزاده لاری, شهرزاد, قبادی مراللو, حسن, عطاران, داود, بصیری, رضا, قانعی, مصطفی   +8 more
core   +1 more source

A liver-X-receptor ligand, T0901317, attenuates IgE production and airway remodeling in chronic asthma model of mice.

PLoS ONE, 2014
The liver-X-receptors have shown anti-inflammatory ability in several animal models of respiratory disease. Our purpose is to investigate the effect of LXR ligand in allergen-induced airway remodeling in mice.
Ying Shi, Xiantao Xu, Yan Tan, Shan Mao, Surong Fang, Wei Gu   +5 more
doaj   +1 more source

Chronic cough due to occupational factors

, 2006
Within the large variety of subtypes of chronic cough, either defined by their clinical or pathogenetic causes, occupational chronic cough may be regarded as one of the most preventable forms of the disease.
Fischer, Axel, Groneberg, Jan David Alexander, Nowak, Dennis, Wussow, Anke   +3 more
core   +1 more source

Air pollution and subclinical airway inflammation in the SALIA cohort study [PDF]

, 2014
The association between long-term exposure to air pollution and local inflammation in the lung has rarely been investigated in the general population of elderly subjects before.
Vierkötter, Andrea, Ursula Krämer, Schulte, Thomas, Tamara Schikowski, Brüning, Thomas, Mohammad Vossoughi, Thomas Brüning, Christian Luckhaus, Christian Herder, Tom Teichert, Luckhaus, Christian, Vossoughi, Mohammad, Barbara Hoffmann, Thomas Schulte, Schikowski, Tamara, Krämer, Ursula, Sugiri, Dorothea, Casjens, Swaantje, Dorothea Sugiri, Hoffmann, Barbara, Andrea Vierkötter, Swaantje Casjens, Teichert, Tom, Monika Raulf-Heimsoth, Raulf-Heimsoth, Monika, Herder, Christian   +25 more
core   +1 more source

Protective Role of Nuclear Factor Erythroid 2-Related Factor 2 Against Respiratory Syncytial Virus and Human Metapneumovirus Infections

Frontiers in Immunology, 2018
The pathogenesis of respiratory syncytial virus (RSV) infections is characterized by lower airway obstruction driven at great extent by the exuberant production of inflammatory cytokines.
Teodora Ivanciuc, Elena Sbrana, Antonella Casola, Antonella Casola, Antonella Casola, Antonella Casola, Roberto P. Garofalo, Roberto P. Garofalo, Roberto P. Garofalo, Roberto P. Garofalo   +9 more
doaj   +1 more source

The role of airway infection in chronic obstructive pulmonary disease

, 2006
PhDThis. thesis examines the role of respiratory bacterial and viral infection in the natural history of Chronic Obstructive Pulmonary Disease. The rationale for this study is basedu pon previous data demonstratingt hat airway bacterial colonisationi s
Wilkinson, Thomas Michael Alan
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Determinação do componente inflamatório das doenças das vias aéreas através do escarro induzido: utilização na prática clínica [PDF]

, 2007
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-graduação em Ciências MédicasIntrodução: Além de um importante instrumento de pesquisa, a celularidade do escarro induzido (EI) vem sendo ...
Moritz, Pablo
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